How clinical pharmacology can take pregnant women and their neonates to its bosom
Pregnant women and their neonates are perhaps the last true therapeutic orphans. The majority of pregnant women take at least one medication to treat a maternal condition but very few pharmacokinetic, pharmacodynamic or clinical trials are currently conducted during pregnancy. As a consequence, evidence to guide effective drug treatment of pregnant women is largely lacking. Off-label use of drugs in neonates is a worldwide issue and of paramount concern. Neonatologists are primarily dependent on clinical experience and data extrapolation from adults, children, and infants to guide optimal drug choice, and to select the most safe and effective dosing regimen. Unfortunately, this has resulted in considerable differences in prescribing practices both between and within countries, for many frequently used drugs in neonates. There is a moral obligation to adopt pregnant women and their neonates into the mainstream of health care research and practice.
Date: 21 May 2024, 17:00
Venue: Mathematical Institute, Woodstock Road OX2 6GG
Speaker: Professor Johannes van den Anker (Children's National Hospital, Washington D.C.)
Organising department: Department of Paediatrics
Organiser contact email address: laura.borg@paediatrics.ox.ac.uk
Booking required?: Required
Booking url: https://forms.office.com/Pages/ResponsePage.aspx?id=G96VzPWXk0-0uv5ouFLPkciHF3bQ-blKlkDomfMVDPtUMzBUT0c0NDZaOUs2REUwWUU1T1dJMzRPNC4u
Booking email: laura.borg@paediatrics.ox.ac.uk
Cost: None
Audience: Members of the University only
Editor: Laura Borg