Sodium channel dysfunction in neurodevelopmental disorders

The Bender Lab is interested in understanding how the brain encodes information at the synaptic, cellular, and network level. We employ a variety of electrophysiological, optical, and genetic techniques to probe information processing across neuronal compartments, from synaptic inputs onto dendritic spines, to the site of action potential initiation in the axon initial segment, to transmitter release in axonal boutons. This work is complemented by biophysical studies of single channels, compartmental modeling, and in vivo recordings and behavior.

Lean more about the Bender Lab: benderlab.ucsf.edu