Regulation of claudin-5 at the blood brain barrier in health and disease
This talk will focus on the critical role played by claudin-5 at the blood-brain barrier (BBB). Claudin-5 is the most enriched tight junction component at the BBB and its dysregulation has been implicated in a range of neurological and neuropsychiatric disorders. Here, the focus will be on understanding how and why claudin-5 becomes disrupted at the BBB. The talk will bring in both pre-clinical and clinical research based approaches to understanding regulation of the BBB in health and disease.
Date:
8 November 2024, 13:00 (Friday, 4th week, Michaelmas 2024)
Venue:
Sherrington Library, off Parks Road OX1 3PT
Venue Details:
Sherrington Building
Speaker:
Professor Matthew Campbell (Trinity College, Dublin)
Organising department:
Department of Physiology, Anatomy and Genetics (DPAG)
Organisers:
Dr Mootaz Salman (DPAG, University of Oxford),
Associate Professor Samira Lakhal-Littleton (DPAG, University of Oxford)
Organiser contact email address:
events@dpag.ox.ac.uk
Host:
Dr Mootaz Salman (DPAG, University of Oxford)
Part of:
DPAG Head of Department Seminar Series
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Hannah Simm