Targeting TCR and Co-Receptor Signaling in T Cell-Mediated Immunity
The potency of the T cell response against pathogens or cancer cells is determined by the signalling output from two distinct classes of immune receptors: the T-cell receptor and co-receptors, which includes activating and inhibitory checkpoint receptors such as CD28 or PD-1 and CTLA-4, respectively. Here, we will provide an update on our latest work in targeting T-cell receptors and inhibitory receptors to modulate T cell responses.
Date: 30 October 2023, 12:00 (Monday, 4th week, Michaelmas 2023)
Venue: Kennedy Institute of Rheumatology, Headington OX3 7FY
Venue Details: Lecture Theatre
Speaker: Dr Ricardo Fernandes (Nuffield Department of Medicine - University of Oxford)
Organising department: Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS)
Organiser: Doris Chan (Kennedy Institute of Rheumatology)
Organiser contact email address: doris.chan@kennedy.ox.ac.uk
Host: Dr Audrey Gerard (The Kennedy Institute of Rheumatology)
Part of: Kennedy Institute Seminars
Booking required?: Not required
Audience: Members of the University only
Editor: Doris Chan