Molecular mechanisms of cortical interneuron diversity and plasticity
To arrange individual meetings with Prof. Oscar Marin, please contact Matthew Buchan (matthew.buchan@chch.ox.ac.uk)
GABAergic interneurons play crucial roles in the regulation of neural circuit activity in the cerebral cortex. A hallmark of cortical interneurons is their remarkable structural and functional diversity, yet the molecular determinants and the precise timing underlying their diversification remain largely unknown. The search for mechanisms controlling the diversity of GABAergic interneurons has primarily focused on the analysis of transcriptional programs in their progenitor cells. In this talk, I will describe how transcriptional programmes, both during embryonic development and in the postnatal brain, regulate the identity of specific classes of cortical interneurons, thereby contributing to the generation of neuronal diversity in the cerebral cortex.
Date: 12 February 2019, 16:00 (Tuesday, 5th week, Hilary 2019)
Venue: Le Gros Clark Building, off South Parks Road OX1 3QX
Venue Details: Large Lecture Theatre
Speaker: Professor Oscar Marin (MRC Centre for Developmental Neurobiology, King’s College London)
Organiser: Cortex Club (University of Oxford)
Organiser contact email address: cortex.club@studentclubs.ox.ac.uk
Part of: Cortex Club - Oxford Neuroscience Society
Topics:
Booking required?: Not required
Audience: Members of the University only
Editor: Marta Blanco pozo