From genotype to phenotype using high-throughput proteomics
For non centre members who would like to attend in person please email isabel.schmidt@well.ox.ac.uk to register. You will need to bring your University card and sign in at reception on arrival.
Understanding the interactions between metabolites and small molecules on one hand, and the proteome on the other, are vital for our understanding of biological phenotypes, metabolism and drug action. In this lecture, I’ll summarize our efforts in developing methods for high-throughput proteomics. I’ll further show examples that illustrate how high-throughput proteomic datasets allow to bridge genome, proteome and metabolome. The results indicate that genome-scale proteomic data opens new avenues for understanding gene function and interactions within biological systems, could impact drug discovery, and lead to a new generation of diagnostic and prognostic tests in medicine.
Date: 2 November 2022, 14:00 (Wednesday, 4th week, Michaelmas 2022)
Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Venue Details: In person: Rooms A&B / Remotely: via Teams. To log in via Teams please put yourself on mute and use the following link: https://teams.microsoft.com/l/meetup-join/19%3ameeting_ZDY4ZGM0ODktNDE0My00MjRiLWEyZDYtNjIxYmFmNzM3NDRk%40thread.v2/0?context=%7b%22Tid%22%3a%22cc95de1b-97f5-4f93-b4ba-fe68b852cf91%22%2c%22Oid%22%3a%22faee8eaf-f9bf-478e-9151-5bbfc3b39a0f%22%7d
Speaker: Professor Markus Ralser (Charitė University Medicine, Berlin)
Organising department: Wellcome Trust Centre for Human Genetics
Organiser: Isabel Schmidt (University of Oxford, Wellcome Centre for Human Genetics)
Organiser contact email address: isabel.schmidt@well.ox.ac.uk
Host: Professor John Todd (Wellcome Trust Centre for Human Genetics, University of Oxford)
Part of: WHG Seminars
Booking required?: Required
Booking email: isabel.schmidt@well.ox.ac.uk
Audience: Members of the University only
Editor: Isabel Schmidt