Seminar by Prof Klaus Hahn 'Mapping live cell circuit dynamics with optogenetics, biosensors and single particle conformational imaging'


This seminar will be held virtually via Zoom and is open to all Oxford University members. Registration with a valid Oxford email address is at: https://medsci.zoom.us/meeting/register/tJ0qcuyppzsoH9Yq1pXxqP-VRi9tEKxUZUmV

The talk will focus on new approaches to quantify and control signaling in living cells. We are probing Rho family GTPase networks in phagocytosis and metastasis by inhibiting or activating key proteins with chemo/optogenetics as we visualize downstream signals. A novel approach to study the conformational changes of individual molecules in live cells will be covered, as will computational approaches to determine causal connections between protein activation events.