Modern research, even that not involving humans or animals directly, can potentially be used in a wide variety of both positive and negative ways. It is the researcher’s responsibility to think about, and plan for the potential impact of their work, and how their work can be carried out in an appropriately ethical and responsible manner. In this course we will discuss a variety of case studies to understand responsible research and innovation principles and practice, and plan our research according to ethical and professional standards, avoiding and mitigating the risks of negative impacts.