Seminar by Prof Chris Denton 'Translating scleroderma: pathogenesis to targeted therapy'
This seminar will be held in person in the Kennedy Institute Lecture Theatre and will also have the option to join online via Zoom https://medsci.zoom.us/meeting/register/tJwufuCqrzktEtPPlHRi_knHEskvO5mBWFKi
Scleroderma, also called systemic sclerosis (SSc), is an autoimmune rheumatic disease with high clinical impact and mortality, due to fibrosis and vascular damage in multiple organs. This seminar will highlight the clinical challenge of SSc and give insights into disease biology provided by studying preclinical models, and through high-dimensional analysis of patient biopsies. The presentation will show how progress in understanding pathogenesis is generating a roadmap for development of targeted therapeutics. Current research efforts are harnessing the intrinsic clinical diversity of SSc, and developing outcome-based disease classification, to improve molecular stratification of cases for clinical practice, and in future trials.
Date: 16 May 2022, 12:00 (Monday, 4th week, Trinity 2022)
Venue: Kennedy Institute of Rheumatology, Headington OX3 7FY
Venue Details: We are returning to in person seminars in the Kennedy Institute Lecture Theatre
Speaker: Prof Chris Denton (UCL)
Organising department: Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS)
Organisers: Ellen Mobbs (Kennedy Institute of Rheumatology), Dr Jelena Bezbradica (The Kennedy Institute of Rheumatology), Professor Irina Udalova (Kennedy Institute of Rheumatology)
Organiser contact email address: ellen.mobbs@kennedy.ox.ac.uk
Host: Professor Christopher Buckley (Kennedy Institute of Rheumatology, University of Oxford)
Part of: Kennedy Institute Seminars
Booking required?: Not required
Audience: Members of the University only
Editors: Elizabeth Thompson, Ellen Mobbs