Brain-wide approaches to neuroplasticity and emotional behavior in the mouse
Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
I will explore the use of brain atlases in the study of the expression of plasticity-related factors, such as perineuronal nets (PNNs), and their application in detecting activation patterns (c-fos mapping) during emotional contagion. Brain atlases provide a detailed anatomical framework to understand the regulation of PNNs, which are crucial for regulating synaptic plasticity and stability. Furthermore, brain atlases enable the identification of activation maps in both demonstrators and observers during emotional contagion, where emotional states are shared between individuals. By examining these activation patterns, we can gain insights into the neural mechanisms underlying empathy and social cognition. The integration of brain atlases with existing datasets offers exciting opportunities to enhance research in this area. Linking these atlases to publicly available gene expression and connectomics datasets allows for more comprehensive analyses.
Date: 3 December 2024, 12:00 (Tuesday, 8th week, Michaelmas 2024)
Venue: Pharmacology, off Mansfield Road OX1 3QT
Venue Details: David Smith Lecture Theatre
Speaker: Professor Tommaso Pizzorusso (Professor of Physiology, Scuola Normale Superiore)
Organising department: Department of Pharmacology
Organiser: Carolyn Thackrah (University of Oxford, Department of Pharmacology)
Organiser contact email address: carolyn.thackrah@pharm.ox.ac.uk
Host: Dr Abhishek Banerjee (Department of Pharmacology, University of Oxford)
Part of: Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars
Booking required?: Not required
Audience: Members of the University only
Editor: Carolyn Thackrah