Join us for this special event as part of National Postdoc Appreciation Week (#NPAW2022) with Pint of Science and Proteintech who will provide refreshments and goody bags!

#NPAW2022 #CelebratePostdocs proteintech pintofscience

“Thymic epithelial cell heterogeneity resolved by Infinity Flow” – Dr Fabian Klein (Postdoctoral researcher at IDRM)

The network of thymic stromal cells provides essential niches with unique molecular cues controlling T-cell development and selection. Recent single-cell RNA-sequencing studies uncovered a large transcriptional heterogeneity among thymic epithelial cells (TEC) demonstrating a previously unappreciated complexity. However, there are only very few cell markers that allow a comparable phenotypic identification of TEC. Here we deconvoluted, by massively parallel flow cytometry and machine learning, known and novel TEC phenotypes into novel subpopulations.

“Messages from the heart” – Dr Naveed Akbar (Postdoctoral researcher at RDM)

Following injury to the heart, millions of immune cells enter the blood. The greater the number of immune cells in the blood following a heart attack, the larger the heart attack and increased risk of mortality. This massive mobilisation is in part mediated by the release of nano-sized envelopes called extracellular vesicles. Naveed will share how proteins on the surface of extracellular vesicles act as an address to mediate across organ communication.

Please register for free in advance at pintofscience.co.uk/event/paw-oxford-idrm