Relations between Turkey and Germany is one the most understudied subjects of Turkey’s foreign policy, despite the fact that there are close to three million Turks living in Germany as result of an immigration started in 1960’s and Germany’s significant share in Turkish economy. Few existing studies examines Turkish-German relations from the perspective of the European Union, since Turkey’s integration to the EU has shaped Ankara’s foreign policy in the last three decades. This article studies what kind of role Political Islam has played in influencing Turkish-German relations since 1960s. Islamist AKP has been ruling Turkey since 2002 and in the last decade experiencing major problems with Germany. While Berlin has been complaining about AKP’s instrumental use of Islamic networks in Germany for Turkey’s interests and criticizing Turkey with the involvement of German domestic affairs, Ankara has been accusing Germany of supporting terrorist groups against Turkey. By examining the development of Islamic networks in Germany with the Turkish immigration since 1960’s and their relations with Islamist parties in Turkey and Muslim Brotherhood network, this study aims to understand the role of the Political Islam in Turkish-German relations.