The Hypoxia Paradox: Friend or Foe for T cell Cancer Therapies?

Iosifina Foskolou, PhD, is a group leader at Sanquin Institute (Amsterdam), specialising in T cell metabolism and cancer immunotherapy. Her lab focuses on improving T cell immunotherapies against solid tumours by better understanding the environments immune cells face in both the tumour microenvironment and lymphoid tissues.

Iosifina holds a DPhil in Oncology from the University of Oxford, where she studied the effects of low oxygen (hypoxia) in solid tumours. She has extensive postdoctoral experience at both Cambridge University and the Karolinska Institute, where she investigated how metabolism can improve cancer immunotherapy.

Iosifina has a robust academic background, and her work has been widely published in peer-reviewed journals, with key papers on T cell function, metabolism, and anti-tumour immunity. Throughout her career, she has secured numerous grants, including a Marie Sklodowska Curie post-doctoral Fellowship.