Diversity and interactions in tumor growth and treatment
Genetic, epigenetic and functional diversity between tumor cells can affect tissue dynamics, tumor growth and treatment dynamics in many ways. I will talk about two examples of diversity. First, I will describe a setup in which non-cell-autonomous interactions led to maintenance of diversity in in vivo breast cancer tumor growth. Second, I will describe an approach to describe the basic features of cancer stem cell and differentiated cancer cell dynamics, which can be used to analyze tumor burden from individual patient trajectories, and to make predictions for treatment continuation, e.g. in leukemia.
Date:
30 September 2016, 12:00
Venue:
Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Venue Details:
Room A/B
Speaker:
Dr Philipp Altrock (Harvard School of Public Health)
Organising department:
Wellcome Trust Centre for Human Genetics
Organisers:
Professor Gil McVean (University of Oxford),
Professor Ian Tomlinson (University of Oxford)
Organiser contact email address:
iant@well.ox.ac.uk
Hosts:
Professor Gil McVean (University of Oxford),
Professor Ian Tomlinson (University of Oxford)
Part of:
WHG Seminars
Topics:
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Emma Jones
