Genomics of Endometriosis: where are we now, and where are we going? (Prof Krina Zondervan, Nuffield Dept of Women's & Reproductive Health)
Genetic studies have the potential to uncover new knowledge on the causes of disease, as well as help understand their complexity through identifying ‘sub-types’ that are underpinned by different pathways of pathogenesis. This information is crucial to inform the identification of novel targets for treatment, as well as methods of (non-invasive) diagnosis. I shall discuss recent progress in the field of endometriosis, covering our collaborative work within the International Endometriosis Genome Consortium, in which we are currently analysing 25 global datasets including >60,000 cases, detailed deep phenotype and comorbidity data, as well as functional ‘omics’ analyses. I will also discuss recent studies of somatic genetic mutations in endometriosis tissue which have received much ‘press’. Lastly, I will discuss how we can translate these genetic results into outcomes that are important to patients and clinicians.
Date: 30 April 2019, 13:00 (Tuesday, 1st week, Trinity 2019)
Venue: John Radcliffe Women's Centre, Headington OX3 9DU
Venue Details: The Anne Anderson Lecture Theatre, Level 3
Speaker: Prof Krina Zondvervan (University of Oxford)
Organising department: Nuffield Department of Women's and Reproductive Health
Booking required?: Not required
Audience: Members of the University only
Editor: Susie Barber