The history and use of DNA-Encoded Libraries in drug discovery
DNA Encoded Libraries (DELs) have become an important and efficient approach for identifying novel chemical entities targeting a range of biomolecular architectures.
Barry Morgan led the development of the DEL platform at Praecis Pharmaceuticals, Boston, joining GSK to lead its continued investment in DEL screening after GSK bought Praecis in 2007. Since that time GSK has gone on to publish several novel chemical entities, now in late phase clinical development. What started as a theory from Sydney Brenner & Richard Lerner has truly come of age as a powerful drug-discovery approach.
Barry is now CSO at HitGen, who continue to build a strong DEL platform based in Chengdu, China.
Date:
12 June 2018, 15:00 (Tuesday, 8th week, Trinity 2018)
Venue:
NDM Building, Headington OX3 7FZ
Venue Details:
TDI seminar room
Speaker:
Dr Barry Morgan (CSO HitGen, Boston, USA)
Organising department:
Structural Genomics Consortium
Organiser:
Natsumi Astley (University of Oxford )
Organiser contact email address:
natsumi.astley@sgc.ox.ac.uk
Host:
Dr Kilian Huber (SGC Oxford)
Part of:
CMD Seminars
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Natsumi Astley
