Novel molecular and generative design platforms for immunotargeting and beyond
Molecular recognition governs immune response. Developing highly specific binding proteins is fundamental to novel theragnostics. We develop a new molecular platform, TRACeR, for peptide-focused targeting of MHCs, with unprecedented specificity. Beyond MHC, we leverage protein generative models to address in silico antibody design. These efforts offer new insights to the immune targeting paradigm and AI modeling strategies. I will present our recent findings on the molecular and software platforms.
Date: 24 May 2024, 14:30 (Friday, 5th week, Trinity 2024)
Venue: Wellcome Trust Centre for Human Genetics, Headington OX3 7BN
Venue Details: Room A+B
Speaker: Dr Possu Huang (Stanford University)
Organising department: CAMS Oxford Institute
Organisers: Dr Ricardo Fernandes (CAMS Oxford Institute), Dr Dannielle Wellington (CAMS Oxford Institute), Mimie Szyk (CAMS Oxford Institute)
Organiser contact email address: coi.admin@ndm.ox.ac.uk
Part of: CAMS Oxford Institute Seminars
Booking required?: Not required
Audience: Members of the University only
Editor: Dannielle Wellington