Prof Samira Lakhal-Littleton is a translational scientist focused on the role of iron in physiology and pathophysiology. She is currently Professor of Physiology, MRC Senior Research Fellow and Tutorial Fellow in Medicine at Brasenose, University of Oxford. After completing her DPhil at Oxford in 2007, she joined the laboratory of Prof Sir Peter Ratcliffe, where she discovered intersections between iron and hypoxia signalling. She then secured a BHF Intermediate Research Fellowship, which allowed her to discover the mechanisms and physiological importance of local iron control in the cardiovascular system. She is now focused on translating her discoveries into the clinic, by joining the dots between clinical data and basic mechanistic understanding of the underlying physiology. She is member of the Royal Society Research Grants Board and UKRI Interdisciplinary Assessment College, and regularly reviews grants for the BHF, MRC and NIH. She is chief investigator of Study of Tissue iron Uptake in iron-Deficient patients following IV iron therapY (STUDY), co-investigator on INtravenous Iron and eryThropoietin to treat Anaemia following CriTical care-2 (INTACT-2), on the Steering Commitee of Effect of INtravenous FERRic Carboxymaltose On mortality and Cardiovascular Morbidity, and Quality of Life in Iron Deficient Patients With Recent Myocardial infarCTion (INFERRCT), and on the scientific advisory board for Prevention of maternal ANaemia to avoid preterm Delivery and other Adverse outcomes (PANDA). Samira has received many awards, most recently the Physiological Society’s Bayliss Starling Prize Lecture. In 2019, she was elected to the board of directors of the International BioIron Society.