Post-translational control of protein homeostasis through regulatory ubiquitylation of the translation machinery
ALL WELCOME
Eric Bennett studies how the proteome is remodelled in response to stress. In particular, his research focuses on the quality control function of the ubiquitin proteasome system (UPS), which is a crucial mechanism of selective protein degradation. His work is relevant to age-related degeneration and disease states, including Parkinson’s Disease and cancer. Topics that his lab investigates include understanding how defective translation products are selectively targeted for degradation, the dynamics of mRNA sequestration into stress granules and proteomic approaches for understanding global UPS function and alterations in response to stress.
Date: 10 September 2015, 11:00
Venue: NDM Building, Headington OX3 7FZ
Venue Details: Basement Seminar Room
Speaker: Dr. Eric Bennett (UCSD)
Organising department: Ludwig Institute for Cancer Research, Oxford Branch
Organisers: Alexandra Ward (University of Oxford, Oxford Ludwig Institute, NDM Experimental Medicine), Mary Muers (Oxford Ludwig Institute, NDM Experimental Medicine)
Organiser contact email address: alexandra.ward@ludwig.ox.ac.uk
Host: Dr. John Christianson (Ludwig Cancer Research, Oxford)
Part of: Ludwig Institute Seminar Series
Topics:
Booking required?: Not required
Audience: Members of the University only
Editor: Mary Muers