Using Genetics to Investigate the Adaptive Immune Responses in Health and Immune-mediated diseases
This seminar will be held using Zoom. Please register here: https://zoom.us/meeting/register/tJcocuupqDMrGtOwJIyKcF2nOHuPMm7F_ZzS
B cells are important in the pathogenesis of many, and perhaps all, immune-mediated diseases. Here we describe methods that characterise the human adaptive immune response by high-throughput sequencing of B cell receptors and single cell transcriptomics. I will describe how we are using these technologies to understand the immune responses across health, autoimmune diseases, immunodeficiencies and cancer, and how we can leverage this knowledge gained across pathologies to direct us towards more targeted therapies.
Date: 5 October 2020, 12:00 (Monday, 0th week, Michaelmas 2020)
Venue: Kennedy Institute of Rheumatology, Headington OX3 7FY
Venue Details: This seminar will be held using Zoom. Please register here: https://zoom.us/meeting/register/tJcocuupqDMrGtOwJIyKcF2nOHuPMm7F_ZzS
Speaker: Dr Rachael Bashford-Rogers (Wellcome Centre for Human Genetics)
Organising department: Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS)
Organisers: Jennifer Pope (Kennedy Institute of Rheumatology), Professor Irina Udalova (Kennedy Institute of Rheumatology)
Organiser contact email address: jennifer.pope@kennedy.ox.ac.uk
Host: Professor Lynn Dustin (Kennedy Institute of Rheumatology)
Part of: Kennedy Institute Seminars
Booking required?: Required
Booking url: https://zoom.us/meeting/register/tJcocuupqDMrGtOwJIyKcF2nOHuPMm7F_ZzS
Audience: Members of the University only
Editor: Jennifer Pope