Breaking symmetry — Cell Polarity Signaling in Axon Guidance and Synapse Formation

Our nervous system is made of many types of neurons wired into complex circuits, which underlie all our behavior. The Zoulab studies the fundamental molecular signaling and cellular mechanisms of axon guidance and synapse formation and how disruption of these normal processes may lead to developmental disorders, such as autism. We also study how neural circuits respond to and recover from traumatic injury, in the hope to promote their repair and return of function.