Engineering Biology for Robust Turing Patterns
Turing patterns have long been proposed as a mechanism for spatial organization in biology, but their relevance remains controversial due to the stringent fine-tuning often required. In this talk, I will present recent efforts to engineer synthetic Turing systems in bacterial colonies, highlighting both successes and limitations. While our three-node gene circuit generates patterns, challenges remain in extending these results to broader contexts. Additionally, I will discuss our exploration of machine learning methods to address the inverse problem of pattern formation, helping the design process down the road. This work addresses the ongoing task in translating theory into robust biological applications, offering insights into both current capabilities and future directions.
Date:
25 October 2024, 11:00 (Friday, 2nd week, Michaelmas 2024)
Venue:
Mathematical Institute, Woodstock Road OX2 6GG
Venue Details:
L5
Speaker:
Prof Robert Endres (Imperial College London)
Organising department:
Mathematical Institute
Organiser:
Sara Jolliffe (University of Oxford)
Organiser contact email address:
sara.jolliffe@maths.ox.ac.uk
Host:
Dr Eamonn Gaffney (University of Oxford)
Part of:
Mathematical Biology and Ecology
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Sara Jolliffe
