Moving towards personalised medicine in sepsis
Please contact admin@cmd.ox.ac.uk for the Zoom link
Sepsis is currently defined as life-threatening organ dysfunction caused by a dysregulated host response to infection and is estimated globally to be responsible for 11 million deaths each year. Despite the therapeutic potential of immunomodulatory therapy, there have been very few successful trials of such agents in patients with this clinical syndrome. I will describe recent efforts to better understand the pathophysiology of sepsis and stratify the maladaptive host response into sub phenotypes associated with specific mechanisms, showing how this can reveal potential targets and biomarkers to guide their therapeutic use.
Date: 19 April 2023, 13:00 (Wednesday, 0th week, Trinity 2023)
Venue: NDM Building, Headington OX3 7FZ
Venue Details: Nuffield Department of Medicine Research Building, Basement Seminar Room, and on Zoom
Speaker: Prof Julian Knight (Wellcome Centre for Human Genetics)
Organising department: Centre for Medicines Discovery
Organiser contact email address: admin@cmd.ox.ac.uk
Host: Brian Marsden (SGC)
Booking required?: Not required
Booking email: admin@cmd.ox.ac.uk
Audience: Members of the University only
Editor: Jack Nicholson