Events this person is organising:

Friday 17 April 2015

• 16:30 - PKMzeta, LTP and memory networks?
  In partnership with the Cortex Club
  Dr Todd Sacktor (SUNY Downstate Medical Center)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 28 April 2015

• 12:00 - Development of the virtual heart for testing the safety of drugs
  Professor Henggui Zhang (School of Physics & Astronomy, University of Manchester)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 5 May 2015

• 12:00 - Idiopathic pulmonary fibrosis – a debilitating lung disease and the discovery of a treatment option
  Dr Florian Gantner (Boeringer Ingelheim )
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Friday 8 May 2015

• 16:00 - The lysosome: from trash can to control center of the cell
  Professor Andrea Ballabio (Scientific Director, TIGEM (Telethon Institute of Genetics and Medicine) and Visiting Professor, Department of Pharmacology)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 12 May 2015

• 12:00 - Differentiating the highs and lows of THC
  Dr Peter McCormick (School of Pharmacy, University of East Anglia)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 19 May 2015

• 12:00 - Mitochondria and lysosomes – the social life of organelles
  Dr Nuno Raimundo (Department of Cellular Biochemistry, Universitätsmedizin Göttingen)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 26 May 2015

• 12:00 - Statins and myopathy
  Dr Sarah Calaghan (Associate Professor in Cardiac Physiology, University of Leeds)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Monday 1 June 2015

• 12:00 - Cardiac iPSCs for disease modeling and drug discovery
  Professor Joseph Wu (Director of the Stanford Cardiovascular Institute)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 2 June 2015

• 12:00 - From rat hippocampal Œtheta to human prefrontal rhythmicity: The first anxiety syndrome biomarker?
  Professor Neil McNaughton (Department of Psychology, University of Otago )
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 9 June 2015

• 12:00 - Activation of ANO1 channels by localised Ca2+ signals in sensory neurons
  Professor Nikita Gamper (School of Biomedical Sciences, University of Leeds)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 16 June 2015

• 12:00 - From human stem cells to human synapses
  Dr Sarah Newey (Royal Society Dorothy Hodgkin Fellow, Department of Pharmacology, University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 13 October 2015

• 12:00 - Tankyrase – a central druggable biotarget in canonical Wnt signaling
  Professor Stefan Krauss (Unit for Cell Signaling, Oslo University Hospital)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 15 October 2015

• 12:00 - Cellular Pacemaking - Crowd Behaviour?
  NOTE THURSDAY DATE
  Professor Dirk van Helden (University of Newcastle, NSW, Australia)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 20 October 2015

• 12:00 - Platelets in time and space: understanding the actions of anti-platelet drugs within the body
  Professor Tim Warner (Barts and the London School of Medicine and Dentistry)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 27 October 2015

• 12:00 - Targeting Redox-Regulation of Cell Mitophagy
  Dr Michelangelo Campenella (Department of Comparative Biomedical Sciences, The Royal Veterinary College)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 3 November 2015

• 12:00 - Biophysics and physiology of anion transport: ClC-7 in lysosomal function and LRRC8 heteromers in cell volume regulation
  Dr Tobias Stauber ( Institute of Chemistry and Biochemistry, Freie Uniersitate Berlin)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 10 November 2015

• 12:00 - Building synaptic connections: it's good to be spontaneous
  Dr Laura Andreae (MRC Centre for Developmental Neurobiology, Kings College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars
• 12:00 - Building synaptic connections: it's good to be spontaneous
  Dr Laura Andreae (MRC Centre for Developmental Neurobiology, Kings College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 17 November 2015

• 12:00 - Discovery of Bcl3 inhibitors as anti-metastatic agents
  Dr Andrea Brancale (Senior Lecturer in Medicinal Chemistry, Cardiff University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 24 November 2015

• 12:00 - Chemical site-selective protein modification for basic biology and drug development
  Dr Gonçalo Bernardes (Royal Society URF, University of Cambridge)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 1 December 2015

• 12:00 - Vascular biology of the TRPM7 chanzyme
  Professor Rhian M Touyz (BHF Glasgow Cardiovascular Research Centre)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 3 December 2015

• 17:00 - Complacency or Change? Which is Oxford’s answer to innovation challenges
  Robert Madelin (Senior Advisor for Innovation in the European Commission)
  Pharmacology Entrepreneurship and Business Seminar Series

Tuesday 19 January 2016

• 12:00 - A therapeutic potential of stem cells for arteriosclerosis
  Professor Qingbo Xu (BHF Centre of Vascular Regeneration, King's College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 26 January 2016

• 12:00 - Visualisation and control of in-vitro models of arrhythmogenesis
  Dr Gil Bub (BHF CRE Intermediate Research Fellow, Oxford Department of Physiology, Anatomy and Genetics)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 2 February 2016

• 12:00 - Ectotherm cardiac Ca2+ signalling in an era of climate change
  Dr Holly Shiels (Faculty of Life Sciences, University of Manchester)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Wednesday 3 February 2016

• 09:00 - The Pulse of British Bioscience
  TBA

Tuesday 9 February 2016

• 12:00 - Cross-frequency coupling between field potential oscillations
  Associate Professor Adriano Tort (Brain Institute, Federal University of Rio Grande do Norte)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 16 February 2016

• 12:00 - Mitochondrial control of heterogeneity in platelets
  Dr Matthew Harper (Cardiovascular Strategic Research Initiative, University of Cambridge)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 23 February 2016

• 12:00 - Structural and biophysical mechanisms of K2P channel gating by polymodal stimuli
  Professor Stephen Tucker (Biological Physics Group, Oxford Department of Physics)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 1 March 2016

• 12:00 - How the sins of your grandparents affect your health: exploring the mechanisms of transgenerational epigenetic inheritance
  Dr Erica Watson (Lecturer in Reproductive Biology, University of Cambridge)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 8 March 2016

• 12:00 - The Achilles’ heel of the heart: the cardiac conduction system
  Professor Mark Boyett (Institute of Cardiovascular Sciences, University of Manchester)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 3 May 2016

• 12:00 - Fuelling the calcium pumps during pancreatitis and pancreatic cancer
  Dr Jason Bruce (Faculty of Life Sciences, University of Manchester)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 10 May 2016

• 12:00 - A fishy story: vascular relaxation mechanisms of n-3 PUFAs
  Dr Alister McNeish (School of Pharmacy, University of Reading)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 17 May 2016

• 12:00 - Dendritic and cellular mechanisms of grid cell firing
  Dr Christoph Schmidt-Hieber (Wolfson Institute for Biomedical Research, University College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 24 May 2016

• 12:00 - The inflammatory response to atherogenic lipid
  Professor Chris O’Callaghan (Centre for Cellular and Molecular Physiology, Nuffield Department of Medicine)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 31 May 2016

• 12:00 - Targeted anticancer drug discovery: chemical tools and clinical candidates
  Professor Ian Collins (Medicinal Chemistry Team, Institute of Cancer Research)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 7 June 2016

• 12:00 - mGluR5 receptors: a promising target for CNS drug discovery?
  Dr Gary Gilmour (In-Vivo Pharmacology, Lilly UK)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 9 June 2016

• 12:00 - The impact of stress on post-transcriptional regulation of the glutamate system
  Dr Monsheel Sodhi (University of Illinois at Chicago)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 14 June 2016

• 12:00 - Optical interrogation of sub-cellular cardiac signalling in atrial and sino-atrial node arrhythmias at high-spatiotemporal resolution
  CANCELLED
  Status: This talk has been cancelled
  Dr Rebecca Burton (Sir Henry Dale Royal Society/Wellcome Trust Fellow, Oxford Department of Pharmacology)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 16 June 2016

• 17:00 - Breakthrough: The Role of Government in Accelerating Science and Technology
  Drinks reception from 6pm
  Nicola Blackwood MP (Chair, Science and Technology Select Committee)
  Pharmacology Entrepreneurship and Business Seminar Series

Thursday 29 September 2016

• 12:00 - From bed to bench side: developmental and translational research pathways for cardiovascular patients
  Professor Raimondo Ascione (Translational Biomedical Research Centre, University of Bristol)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Wednesday 5 October 2016

• 12:00 - Multi-scale integration of cardiac excitation: from ion-channel molecular structure to the human heart
  Professor Yoram Rudy (Washington University in St. Louis)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 11 October 2016

• 12:00 - Insulin sensitisation in the endothelium: all that glitters isn’t gold
  Professor Mark Kearney (Leeds Institute of Cardiovascular and Metabolic Medicine)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 25 October 2016

• 12:00 - Computational studies of bacterial membrane proteins: potential targets for novel antibiotics
  Dr Phillip J Stansfeld (Department of Biochemistry, University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 15 November 2016

• 12:00 - New insights into pain mechanisms
  Professor John Wood (Wolfson Institute for Biomedical Research, University College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 29 November 2016

• 12:00 - Competition and cooperation in the striatum: of nitric oxide and acetylcholine
  CANCELLED
  Dr Enrico Bracci (Department of Psychology, University of Sheffield)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 17 January 2017

• 12:00 - Agonist efficacy in the Cys-loop superfamily of channels: the single molecule view
  Professor Lucia Sivilotti (AJ Clark Professor of Pharmacology, UCL)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Wednesday 8 February 2017

• 12:00 - Molecular mechanisms of synaptic transmission
  12TH DAVID SMITH LECTURE
  Professsor Thomas Südhof (Department of Molecular and Cellular Physiology, Stanford University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 21 February 2017

• 11:00 - The calcium-sensing receptor in physiology and disease
  Professor Daniela Riccardi (Deputy Head, Cardiff School of Biosciences)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 28 February 2017

• 12:00 - Redox-dependent mechanisms of homocysteine metabolism
  Cancelled
  Status: This talk has been cancelled
  Dr Alison Brewer (Faculty of Life Sciences and Medicine, King’s College London)

Thursday 2 March 2017

• 12:00 - Title TBA
  CANCELLED
  Status: This talk has been cancelled
  Mike Standing (Deliotte)
  Pharmacology Entrepreneurship and Business Seminar Series

Tuesday 7 March 2017

• 12:00 - Normal and abnormal transmural electrophysiology in the intact mammalian ventricle
  Professor Godfrey Smith (Institute of Cardiovascular and Medical Sciences, University of Glasgow)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 23 March 2017

• 12:00 - Deregulation of a novel NGF metabolic pathway as the cause of Cholinergic atrophy in Alzheimer’s
  Professor Claudio Cuello (McGill University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 25 April 2017

• 12:00 - Novel regulators of adverse cardiac remodelling post-myocardial infarction
  Dr Christopher Loughrey (Institute of Cardiovascular & Medical Sciences, University of Glasgow)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 2 May 2017

• 12:00 - The ins and outs of calcium-induced calcium release
  Professor Mark Cannell (School of Physiology & Pharmacology, University of Bristol)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 16 May 2017

• 12:00 - Misfolding of Tau and Alpha-Synuclein: towards a therapeutic target in neurodegenerative diseases
  Professor Maria Grazia Spillantini FRS (Department of Clinical Neurosciences, University of Cambridge)

Tuesday 23 May 2017

• 12:00 - Transcriptional architecture of cortical GABAergic neuron types
  Professor Z Josh Huang (Cold Spring Harbor Laboratory)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 8 June 2017

• 12:00 - Sino-British Scientific and Technological Innovation: Cooperation and Prospects
  Joint seminar with the Oxford Chinese Life Scientists Society (OCLSS)
  Sunan Jiang (Minister Counsellor, (Science & Technology), Chinese Embassy)

Tuesday 10 October 2017

• 12:00 - Outsmarting the acidic challenge: emerging concepts of acid-handling in cancer
  Professor Pawel Swietach (Department of Physiology, Anatomy and Genetics (DPAG), University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 24 October 2017

• 12:00 - Like SNPs in the night: psychiatric genetics, neural circuits and sleep
  Dr Matt Jones (University of Bristol)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 31 October 2017

• 12:00 - New approaches to the crisis in finding therapies for neurodegenerative diseases underlying dementia
  Dr John Davis (University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 14 November 2017

• 12:00 - Neurocardiac interaction in malignant ventricular arrhythmias and sudden cardiac death
  Professor André Ng (University of Leicester BHF Cardiovascular Research Centre)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 21 November 2017

• 12:00 - In vivo screening identifies novel host regulators of metastatic colonisation
  Dr Anneliese Speak (Experimental Cancer Genetics Group, Wellcome Trust Sanger Institute)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 5 December 2017

• 12:00 - Coding of space and time in entorhinal cortex
  Professor Michael Hasselmo (Department of Psychological and Brain Science, Boston University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 16 January 2018

• 12:00 - The neural circuitry underlying spatial pattern detection in the retina
  Dr Jamie Johnston (Faculty of Biological Sciences, University of Leeds)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 23 January 2018

• 12:00 - Neurons, networks and circadian rhythms
  Professor Hugh Piggins (Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 30 January 2018

• 12:00 - A molecular fingerprint for colonic sensory neurones and life lessons from the naked mole-rat
  Dr Ewan St John Smith (Department of Pharmacology, University of Cambridge)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 6 February 2018

• 12:00 - The role of ATP-sensitive K+ channels in the cardiovascular system
  Professor Andrew Tinker (William Harvey Research Institute, Barts and the London School of Medicine )
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 13 February 2018

• 12:00 - Cardioprotection: why do we struggle to translate good pre-clinical data to patient benefit?
  Dr Rich Rainbow (Department of Cardiovascular Sciences, University of Leicester)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 20 February 2018

• 12:00 - Genomics of neurodegenerative diseases
  Professor John Hardy (Department of Molecular Neuroscience, UCL)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 27 February 2018

• 12:00 - The role of heme iron in ion channel regulation
  CANCELLED*CANCELLED*CANCELLED
  Status: This talk has been cancelled
  Dr Nina Storey (Department of Molecular and Cell Biology, University of Leicester)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 6 March 2018

• 12:00 - Signalling to and from IP3 receptors
  Professor Colin W Taylor (Wellcome Trust Senior Investigator, University of Cambridge)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 8 March 2018

• 12:00 - Natural product synthesis towards small-molecule probes and drugs
  NOTE THURSDAY DATE
  Professor Tao Ye (Peking University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 29 March 2018

• 12:30 - Understanding the neurochemical basis of addictive behaviors with optogenetics
  Dr Evgeny Budygin (Wake Forest School of Medicine, Winston Salem NC)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 24 April 2018

• 12:00 - Multiple signalling roles of calcium-dependent potassium currents in central neurons
  Professor Paola Pedarzani (Neuroscience, Physiology and Pharmacology, UCL)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 1 May 2018

• 12:00 - Identification of a Vamp2 transmembrane mutation in screens affecting mouse sleep and behaviour
  Dr Pat Nolan (Neurobehavioural Genetics Group, MRC Harwell)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 8 May 2018

• 12:00 - Ensemble coding of behavior in amygdala circuits
  13th David Smith Lecture
  Professor Andreas Lüthi (Friedrich Miescher Institute for Biomedical Research)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 15 May 2018

• 12:00 - Balancing the brain’s energy supply: neurovascular coupling in health and disease
  Dr Catherine Hall (School of Psychology, University of Sussex)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 22 May 2018

• 12:00 - Activation and regulation of the calcium-dependent chloride channel TMEM16A
  Dr Jorge Arreola (Institute of Physics, UASLP, San Luis Potosi, Mexico)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 29 May 2018

• 12:00 - Controlling ion channels with fat: the physiological role of S-acylation
  Professor Mike Shipston (Biomedical Sciences, University of Edinburgh)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 5 June 2018

• 12:00 - Up the nanojunction: calcium signals and their corruption
  Professor Mark Evans (Centres for Discovery Brain and Cardiovascular Sciences, University of Edinburgh)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 12 June 2018

• 12:00 - Left-right brain hemisphere asymmetry of synaptic plasticity in the hippocampus
  Professor Ryuichi Shigemoto (Institute of Science and Technology Austria (IST Austria))
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Friday 27 July 2018

• 12:00 - An electrophysiological approach to analyse TRPML2 in endolysosomes
  Dr Cheng-Chang (Maxo) Chen (Department of Pharmacology, LMU Munich)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 18 September 2018

• 12:00 - Peroxynitrite-induced impairment of endothelial TRPV4 channel function and vasodilation in obesity
  Assistant Professor Swapnil Sonkusare (University of Virginia – School of Medicine)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 25 September 2018

• 12:00 - Congenital myopathies linked to recessive RyR1 mutations: pathophysiology and treatment
  Dr Francesco Zorzato (University of Basel)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 9 October 2018

• 12:00 - Overlapping mechanisms of sleep, sedation and thermoregulation
  Professor Nick Franks (Department of Life Sciences, Imperial College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 16 October 2018

• 12:00 - Insulin action - a pancreatic islet perspective
  Professor Patrik Rorsman (University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 23 October 2018

• 12:00 - Seeing is believing: probing protein assembly and protein-ligand interactions by single molecule spectroscopy and imaging
  Dr Liming Ying (National Heart and Lung Institute, Imperial College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 30 October 2018

• 12:00 - Ryanodine receptor - calcium release channel complex in cardiac physiology and disease
  Dr Spyros Zissimopoulos (BHF Senior Research Fellow, Swansea University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 6 November 2018

• 12:00 - Network-driven drug discovery - what is it and why do we need it?
  Alan Whitmore (Head of Discovery Biology, E-Therapeutics plc)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 13 November 2018

• 12:00 - Lines of communication: the role of lysosomal membrane contact sites in cholesterol homeostasis
  Dr Emily Eden (Senior Reseach Fellow, Faculty of Brain Sciences, UCL)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 20 November 2018

• 12:00 - Radiation therapy and bladder dysfunction
  Professor Karen McCloskey (Centre for Cancer Research and Cell Biology, Queen’s University Belfast)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 27 November 2018

• 12:00 - Septo-hippocampal circuitry beyond theta generation: how hippocampal spatial code is tuned by septal activity
  Dr Marian Tsanov (Wellcome Trust RCD Fellow, Trinity College Dublin)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 15 January 2019

• 12:00 - Making neurons stronger: heavy handling of neurological disease
  Dr Mikhail Shchepinov (Chief Scientific Officer, Retrotope Inc)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 22 January 2019

• 12:00 - Unravelling cellular Ca2+ signalling in heart disease: adventures in space, time and noise
  Professor Christopher George (Swansea University Medical School)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 29 January 2019

• 12:00 - Cystic fibrosis: restoring function to faulty channels with small molecules
  Professor David Sheppard (School of Physiology, Pharmacology and Neuroscience, Unviersity of Bristol)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Monday 4 February 2019

• 12:00 - Nerve growth factor regulation and Alzheimer’s pathology: a potential source of new therapies and diagnostic tools
  Rowan Pentz (Department of Pharmacology and Therapeutics, McGill University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 5 February 2019

• 12:00 - Nutrient sensing in the gut in the regulation of appetite
  Professor Kevin Murphy (Faculty of Medicine, Imperial College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 12 February 2019

• 12:00 - Regulation of neurotransmitter release by Ca2+-sensitive oligomerisation of Synaptotagmin 1
  : Professor Kirill Volynski (Institute of Neurology, University College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 19 February 2019

• 12:00 - Capturing drug targets in flight
  CANCELLED
  Status: This talk has been cancelled
  Professor Dame Carol Robinson (University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 26 February 2019

• 12:00 - Modelling neurodevelopmental disorders using stem cell technology
  CANCELLED
  Status: This talk has been cancelled
  Associate Professor Andrea Németh (Nuffield Department of Clinical Neurosciences)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 5 March 2019

• 12:00 - New insights into the mechanisms regulating megakaryocyte development and platelet production
  Dr Alexandra Mazharian (University of Birmingham)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 12 March 2019

• 12:00 - Molecular motions of the CFTR chloride ion channel protein during pore opening
  Professor László Csanády (Department of Medical Biochemistry, Semmelweis University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Friday 15 March 2019

• 12:00 - It's complicated - calcium channels, dopamine neurons, and Parkinson's disease
  Professor Birgit Liss (Institute of Applied Physiology, University of Ulm)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 19 March 2019

• 12:00 - The multifaceted functions of junctophilin-2 in normal and failing hearts
  Professor Long-Sheng Song (Department of Internal Medicine, University of Iowa)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 7 May 2019

• 12:00 - Role of PIP2-binding protein MARCKS in regulating vascular contractility
  Professsor Anthony Albert (Molecular & Clinical Sciences Research Institute, St George’s University London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Friday 10 May 2019

• 12:00 - Approaches for measuring the brain’s chemistry a cell at a time
  Professor Jonathan Sweedler (Department of Chemistry, University of Illinois)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 14 May 2019

• 12:00 - Regulation of intracellular sodium in the heart
  Dr Davor Pavlovic (Institute of Cardiovascular Sciences, University of Birmingham)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 21 May 2019

• 12:00 - Therapeutic vasculoprotection, autoimmune disease and premature atherosclerosis
  Professor Justin Mason (Vascular Sciences Unit, Imperial College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 28 May 2019

• 12:00 - Inhibition that’s exciting in the brain
  14th David Smith Lecture
  Professor Hannah Monyer (Center for Neurosciences, Universität Heidelburg)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 30 May 2019

• 12:30 - Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor
  Note 12.30pm start on a THURSDAY
  Dr Massimiliano Stagi (Institute of Translational Medicine, University of Liverpool)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 4 June 2019

• 12:00 - Take the long way home: axonal transport, organelle dynamics and neurodegenerative diseases
  CANCELLED
  Status: This talk has been cancelled
  Professor Giampietro Schiavo (Sobell Department of Motor Neuroscience and Movement Disorders, UCL-Institute of Neurology)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 11 June 2019

• 12:00 - Activation and function of Piezo1 channels in endothelial cells: new way to interpret mechanic force in cardiovascular system
  Dr Jian Shi (British Heart Foundation Intermediate Fellow, University of Leeds)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 18 June 2019

• 12:00 - My life as a secondhand (repurposed) drug discoverer
  Professor Michael Parnham (Fraunhofer Institute for Molecular Biology & Applied Ecology)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 27 June 2019

• 12:00 - Plasticity in the central and peripheral nervous systems and its role in disorders of the brain and heart
  Note Thursday date
  Associate Professor Johanna Montgommery (Department of Physiology, University of Auckland)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 20 August 2019

• 12:00 - Mitochondrial transport, quality control, and energy homeostasis in nerve degeneration and regeneration
  Dr Zu-Hang Sheng (National Institute of Neurological Disorders and Stroke, NIH )
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 19 September 2019

• 12:00 - CaMKII in heart failure and arrhythmias
  Professor Donald Bers (University of California, Davis USA)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Friday 27 September 2019

• 12:00 - Brain-body cross-talk after traumatic brain injury: gut, lung, immune and other systemic interactions
  Dr Alan Faden (Director, Center for Shock, Trauma and Anesthesiology Research (STAR), University of Maryland)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 15 October 2019

• 12:00 - Malignant hyperthermia, a clinician’s nightmare and a scientist’s delight: personal insights after 40 years of investigation
  Dr Paul Allen (Translational and Clinical Muscle Disease Research Center, Brigham and Women’s Hospital)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 22 October 2019

• 12:00 - Pak2 regulation of ER stress in cardioprotection
  Professor Xin Wang (Cardiovascular Sciences Division, University of Manchester)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 29 October 2019

• 12:00 - Micronutrients as treatments for psychiatric disorders – rethinking the scientific paradigm
  Professor Julia Rucklidge (Professor of Clinical Psychology, University of Canterbury)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 5 November 2019

• 12:00 - The gut, the brain and energy metabolism: the role of ABCC5 in metabolism and neuron excitability
  Associate Professor Heidi de Wet (Oxford Center for Gene Function, DPAG, University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 12 November 2019

• 12:00 - Regulating intracellular Ca2+ release in cardiac muscle
  Associate Professor Dirk Gillespie (Department of Physiology and Biophysics, Rush University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 19 November 2019

• 12:00 - Regulation of mammalian autophagy
  Dr Sharon A Tooze (Molecular Cell Biology of Autophagy Laboratory, The Francis Crick Institute)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 26 November 2019

• 12:00 - Remembering the mammillary bodies: from relay to orchestrator
  CANCELLED
  Status: This talk has been cancelled
  Professor Seralynne Vann (School of Psychology, Cardiff University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 3 December 2019

• 12:00 - A delivery service for maintaining Phosphoinositides levels during Phospholipase C signalling
  Professor Shamshad Cockcroft (Division of Biosciences, University College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 21 January 2020

• 12:00 - How transcription factor interaction networks control gene expression programs
  Dr Giovanna Zinzalla (Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 28 January 2020

• 12:00 - Of mice (and rats) and men: assessing and correcting dysfunction in models of fragile X syndrome
  Professor David Wyllie (Centre for Discovery Brain Sciences, University of Edinburgh)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 4 February 2020

• 12:00 - Alzheimer's disease: the interaction between amyloid beta, synapses and microglia
  Professor Frances Edwards (University College London (UCL))
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 11 February 2020

• 12:00 - Is there neurogenesis in the adult spinal cord?
  Dr Susan Deuchars (School of Biomedical Sciences, University of Leeds)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 18 February 2020

• 12:00 - Damn the compass, full steam ahead! Disease model validity and the problem of drug discovery
  Professor Jack Scannell (JW Scannell Analytics Ltd and School of Social and Political Sciences, University of Edinburgh)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 25 February 2020

• 12:00 - Control of vascular stability and inflammation-induced leakage via integrins
  Associate Professor Pipsa Saharinen (Translational Cancer Medicine Program, University of Helsinki)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 3 March 2020

• 12:00 - Mechanotransduction is required for maintaining the identity of mature cochlear IHCs and their innervation
  Professor Walter Marcotti (Department of Biomedical Science, University of Sheffield)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 10 March 2020

• 12:00 - The enlightened heart: optogenetic approaches to treat and understand cardiac arrhythmia
  Professor Philipp Sasse (Institute for Physiology, University of Bonn)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 13 October 2020

• 12:00 - Is Oxford getting better at producing new medicines for patients?
  CANCELLED
  Status: This talk has been cancelled
  Professor Chas Bountra (NDM)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 27 October 2020

• 13:00 - Targeting mitochondrial metabolism for early detection and treatment of doxorubicin-induced cardiotoxicity (KT) AND Targeting bacterial DNA repair to combat antibiotic resistance (TLH)
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Various Speakers
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 10 November 2020

• 13:00 - Dynamic readout of nucleic acids by proteins
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Marcin Nowotny (Laboratory of Protein Structure, International Institute of Molecular and Cell Biology, Warsaw)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 24 November 2020

• 13:00 - Evaluation of endogenous neurotransmitter release in the human brain using PET
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Ilan Rabiner (EVP Head of Translational Imaging, Invicro)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 2 February 2021

• 13:00 - Is Oxford getting better at producing new medicines for patients?
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Chas Bountra (Structural Genomic Consortium)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 16 February 2021

• 13:00 - Signalling to and from IP3 receptors
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Colin Taylor (Department of Pharmacology, University of Cambridge)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 2 March 2021

• 13:00 - Cardiovascular mechanisms of CGRP – from discovery until today
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Susan Brain, Head of Vascular Biology and Inflammation (King's College, London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 12 October 2021

• 12:00 - Hypothalamic glutamatergic-vasopressin ascending projections involved in anxiety, avoidance and motivated behaviours
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Limei Zhang (Department of Physiology, National Autonomous University of Mexico)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 26 October 2021

• 12:00 - Mass spectrometry and its role in membrane protein drug discovery
  Professor Dame Carol Robinson (University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 2 November 2021

• 12:00 - 4D Pharmacology - therapeutics to control time
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Stuart Maudsley (Receptor Biology Lab, University of Antwerp)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 9 November 2021

• 12:00 - Transcriptomic basis of remodeling in heart failure
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Igor Efimov (Alisann and Terry Collins Professor of Biomedical Engineering, George Washington University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 16 November 2021

• 13:00 - Regulation of the striatal network by acetylcholine/glutamate cotransmission: linking together compulsion, addiction and eating disorders
  NOTE SEMINAR WILL BE AT 1PM. E-mail carolyn.thackrah@pharm.ox.ac.uk for joning instructions
  Professor Salah El Mestikawy (Douglas Research Centre, McGill University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 23 November 2021

• 12:00 - Endosomes and lysosomes: platforms for multimolecular signalling and amyloidogenesis in health and disease
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Clive Wilson (DPAG, University of Oxford)

Tuesday 30 November 2021

• 12:00 - Local control of protein synthesis in cortical wiring
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Oscar Marin (MRC Centre for Neurodevelopmental Disorders, King's College London)

Tuesday 18 January 2022

• 12:00 - Mechanisms of rapid antidepressant action
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Lisa Monteggia (Vanderbilt Brain Institute, Vanderbilt University, Nashville)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 25 January 2022

• 12:00 - Adenosine integrates light and sleep signalling for regulation of circadian timing
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Associate Professor Sridhar Vasudevan (Department of Pharmacology, University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 1 February 2022

• 12:00 - Mimicking protein-protein interactions in persistent bacteria
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Anna Barnard (Sir Henry Dale Fellow, Molecular Sciences Research Hub, Imperial College)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 8 February 2022

• 12:00 - Understanding cellular and molecular mechanisms of anthracycline cardiotoxicity
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Margaret Cunningham (Strathclyde Institute for Pharmacy and Biomedical Sciences (SIPBS))
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 15 February 2022

• 12:00 - A dual potassium channel dysfunction underlies small vessel disease of the brain in Alzheimer's Dementia
  HYDRID seminar - join us in person or e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Adam Greenstein (Division of Cardiovascular Sciences, University of Manchester)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 22 February 2022

• 12:00 - Microcircuit determinants of hippocampal oscillatory activity
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Liset M de la Prida (Instituto Cajal - CSIC)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 1 March 2022

• 12:00 - Development of the ventricular conduction system: how the heart gains its rhythm
  E-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Lucile Miquerol (Developmental Biology Institute of Marseille (IBDM), Aix-Marseille Université)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 8 March 2022

• 12:00 - Building hybrid biological-digital twins of cardiomyocytes using dynamic clamping
  E-mali carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Teun de Boer (Associate Professor, Deparment of Medical Physiology, UMC Utrecht)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 26 April 2022

• 12:00 - Imaging tumour metabolism – From mouse to man
  Join us in person or attend remotely - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Kevin Brindle FMedSci FRS (CRUK Cambridge Institute)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 3 May 2022

• 12:00 - There's a time and a place - neuronal activity and noise in synaptic wiring specificity
  Join us in person or attend remotely - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Dr Laura Andreae (MRC Centre for Developmental Neurobiology, Kings College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 10 May 2022

• 12:00 - Pharmacology Research Staff Society seminar: cutting-edge research in cardiovascular pharmacology
  Join us in person or remotely via Teams - e-mail david.priestman@pharm.ox.ac.uk or jimmy.martin@pharm.ox.ac.uk for joining instructions
  Various Speakers
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 17 May 2022

• 12:00 - Understanding TRPC1/4/5 channels through chemical/structural biology
  Join us in person or attend remotely - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Associate Professor Robin Bon (School of Medicine, University of Leeds)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 24 May 2022

• 12:00 - The Ca2+-gated Cl- channel TMEM16A is a crucial amplifier of capillary pericyte contraction in the normal and ischemic brain
  Join us in person or remotely via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Paolo Tammaro (Department of Pharmacology, University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 7 June 2022

• 12:00 - Genetic variation, transcriptional regulation and epigenetics underlying heart rhythm
  Join us in person or attend remotely - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Vincent Christoffels (Cardiovascular Sciences, Amsterdam UMC)

Tuesday 14 June 2022

• 12:00 - Memories of long term potentiation
  15TH DAVID SMITH LECTURE Join us in person or attend remotely - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Tim Bliss (Visiting Professor at UCL and the Frontier Institutes of Science and Technology, Xi’an Jiaotong University, China)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 11 October 2022

• 12:00 - Lysosomal signaling in metabolic adaptation and tumorigenesis
  Please join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Andrea Ballabio (Scientific Director, TIGEM (Telethon Institute of Genetics and Medicine) and Visiting Professor, Department of Pharmacology)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 18 October 2022

• 12:00 - How is the circadian clock set to the right time
  Join us in person in the David Smith Lecture Theatre or join remotely via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Associate Professor Aarti Jagannath (Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neuroscience)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 25 October 2022

• 12:00 - The role of the two pore channels in melanoma
  Join in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Associate Professor John Parrington (Department of Pharmacology, University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 1 November 2022

• 12:00 - How best to explore chemical space for bioactive molecular discovery?
  Join in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Adam Nelson (School of Chemistry, University of Leeds and Head of High-Throughput Molecule Discovery at Rosalind Franklin Institute (RFI), Harwell)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 8 November 2022

• 12:00 - ‘Drug development of new synthetic thyroid hormone derivatives for metabolic/neurodegenerative diseases’ (Dr Massimiliano Runfola) AND A mechanistic investigation of lithium’s neuropharmacological and metabolic actions (Dr Brooke Prakash)
  Join in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Various Speakers
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 15 November 2022

• 12:00 - Where targeting DNA can take you …
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Isabel Rozas (Drug Disovery and Medicinal Chemistry, Trinity College, Dublin)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 22 November 2022

• 12:00 - Investigating the neuropsychological effects of antidepressants in a translational rodent model
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  TBA
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 29 November 2022

• 12:00 - The glycobiology of Guillain-Barre syndrome: from Alexander to Zika
  16th David Smith Lecture. Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Hugh Willison (Institute of Infection, Immunity and Inflammation, University of Glasgow)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 24 January 2023

• 12:00 - Adaptive plasticity of central synapses and their astroglial environment
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Dmitri Rusakov (UCL Queen Square Institute of Neurology)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 31 January 2023

• 12:00 - Opioid pharmacology: from molecule to coffin
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Professor Graeme Henderson (School of Physiology, Pharmacology and Neuroscience, University of Bristol)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 7 February 2023

• 12:00 - Using long-read RNA-sequencing to study the hidden transcriptome at the GBA1/GBAP1 locus with implications for our understanding of its role in Parkinson's disease
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Professor Mina Ryton (Genetics and Genomic Medicine, UCL GOS Institute of Child Health)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 14 February 2023

• 12:00 - Intracellular chloride regulation mediates local sleep pressure in the cortex’ Dr Hannah Alfonsa, Akerman Group AND The role of NPC1-PMCA2 complex in Niemann-Pick disease type C’ Dr Maria Fernandez-Suarez, Platt Group
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Various Speakers
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 21 February 2023

• 12:00 - Non-natural amino acids and bio-orthogonal ligations in peptide and protein engineering
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Assistant Professor Marina Rubini (School of Chemistry, University College Dublin)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 28 February 2023

• 12:00 - Mechanisms and inhibition of multidrug transporters
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Hendrik van Veen (Cambridge Infectious Diseases, University of Cambridge)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 7 March 2023

• 12:00 - Building a flexible sensory cortex: Function and dysfunction
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Dr Abhishek Banerjee (Newcastle University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 25 April 2023

• 12:00 - Preventing mitochondrial superoxide production as a therapeutic strategy in heart attack and stroke
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Mike Murphy (MRC Mitochondrial Biology Unit, University of Cambridge)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 2 May 2023

• 12:00 - Following the cues - how do sound and light cues impact risky decision making?
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Catharine Winstanley (The University of British Columbia)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 9 May 2023

• 12:00 - When the heart skips a beat for the brain: a new approach for the treatment of cardiac arrhythmias linked to mutations in the cardiac ryanodine receptor
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Charalampos Sigalas (Department of Pharmacology, University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 16 May 2023

• 12:00 - ‘Insights into PV+ interneurons’ physiology in cognitive dysfunction’ - Dr Sara Hizaji, Blascko Fellow, Viney group AND ‘How to drug the “undruggables”’ - Dr Carole Bataille, Russell group
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  TBA
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 23 May 2023

• 12:00 - Exploring TCR and co-receptor signalling in T cells using engineered ligands
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Ricardo Fernandes (CAMS Oxford Institute, University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 30 May 2023

• 12:00 - Towards systems biology of human sleep/wake cycles: phosphorylation hypothesis of sleep
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Hiroki Ueda (School of Medicine, University of Tokyo and RIKEN Center for Biosystems Dynamics Research (BDR))
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 6 June 2023

• 12:00 - Pharmacological targets in the treatment of LUTS focusing on microvasculature and spontaneous contractions of muscle components including muscularis mucosae
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Hikaru Hashitani (Department of Cell Physiology, Nagoya City University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Wednesday 14 June 2023

• 12:00 - Drugs and trafficking: lessons from voltage-gated calcium channels
  17TH DAVID SMITH LECTURE Join us in person or via Teams Live - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Annette Dolphin (Department of Neuroscience, Physiology and Pharmacology, UCL)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Wednesday 27 September 2023

• 12:00 - New therapeutic approaches to tuberculosis
  CANCELLED
  Status: This talk has been cancelled
  Professor Lalita Ramakrishnan (University of Cambridge)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 10 October 2023

• 12:00 - A role for IL-3 in brain health and disease
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructiions
  Dr Abi Yates (Icahn School of Medicine at Mount Sinai, New York)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 17 October 2023

• 12:00 - Cortex and beyond: an evolutionary perspective on visual circuits for action
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Assistant Professor Sarah Ruediger (Wellcome Trust CDA Fellow, University College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 24 October 2023

• 12:00 - Understanding the link between inflammation and immunity in ageing
  Join us in person or via Teams - e-mail jimmy.martin@pharm.ox.ac.uk for joining instructions
  Dr Roel De Maeyer (Oxford-BMS Fellow, NDORMS)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 31 October 2023

• 12:00 - Pharmacology of platelet immune receptors: mechanisms of activation and development of therapeutics
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Professor Steve Watson (Institute of Cardiovascular Sciences, University of Birmingham)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 7 November 2023

• 12:00 - LINGO proteins – novel regulatory subunits of BK channels
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Professor Mark Hollywood (Smooth Muscle Research Centre, Dundalk Institute of Technology)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 14 November 2023

• 12:00 - 'Chemical biology tools: from target validation to developing novel antibiotics' - Dr Adam Thomas AND 'Linking memories: Investigating the synaptic tagging and capture hypothesis in freely-exploring mice' - Yuki Sakai
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Various Speakers
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 21 November 2023

• 12:00 - Imaging the IR injured beating heart coronary microcirculation in vivo
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining details
  Dr Neena Kalia (Institute of Cardiovascular Sciences , University of Birmingham)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 28 November 2023

• 12:00 - Daily regulation of osmostasis and mammalian cell function
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr John O’Neill (MRC Laboratory of Molecular Biology, University of Cambridge)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Friday 1 December 2023

• 12:00 - Brewing up new mechanisms controlling T-cell receptor signaling
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Marcus John Curtis Long (Senior Postdoctoral Researcher, University of Lausanne)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 23 January 2024

• 12:00 - Not just an affair of the heart: a look at ERG channels and Kv7 channels in smooth muscle
  Join us in person or remotely via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Iain Greenwood (Vascular Biology Research Centre, University College London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 30 January 2024

• 12:00 - 'Effects of chronic hyperglycaemia and glucokinase activation/inhibition on pancreatic β-cell function’ - Dr Matthew Lloyd AND 'Chemical modifications of nanobodies’ - Dimitris Mamalis
  Join us in person or remotely via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Various Speakers
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 6 February 2024

• 12:00 - Protons to patients: insights into the role of the chloride-proton antiporter ClC-7 in lysosomal biology
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Joseph Mindell (Membrane Transport Biophysics Section, NIH)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 20 February 2024

• 12:00 - The cortical regulation of sleep
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Lukas Krone (Sir Henry Wellcome Fellow, Department of Physiology, Anatomy and Genetics (DPAG))
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 27 February 2024

• 12:00 - Assembly of axonal domains that promote nerve conduction: the Axon Initial Segment and the node of Ranvier
  Join us in person or remotely via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Peter Brophy (Centre for Discovery Brain Sciences, University of Edinburgh)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 5 March 2024

• 12:00 - The impact of microglia on neuronal function and brain plasticity
  Join us in person or remotely via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Assistant Professor Sandra Siegert (Institute of Science and Technology Austria (ISTA))
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 23 April 2024

• 12:00 - PIEZO1 force sensor in cardiovascular health and its potential as a drug target
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Professor David Beech (School of Medicine, University of Leeds)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 30 April 2024

• 12:00 - Forces in vessels: how mechanosensors initiate atherosclerosis in arteries
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Professor Ellie Tzima (Radcliffe Department of Medicine, University of Oxford)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 7 May 2024

• 12:00 - Letting the (B)CAT out of the bag - SGLT2i-cardioprotection in doxorubicin-induced heart failure
  Join us in person or remotely via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Kerstin Timm (BHF CRE Intermediate Transition Research Fellow and Career Development Fellow)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars
• 12:00 - Oxford Biomedical Research Centre Drug Discovery Subtheme: opportunity for collaborations
  This talk has been cancelled and replaced with 'Letting the (B)CAT out of the bag - SGLT2i-cardioprotection in doxorubicin-induced heart failure' - presented by Dr Kerstin Timm
  Status: This talk has been cancelled
  Professor Barbara Casadei (Radcliffe Department of Medicine)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 14 May 2024

• 12:00 - Sex differences in neural control of urethral smooth muscle
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Associate Professor Bernard Drumm (Dundalk Institute of Technology)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 21 May 2024

• 12:00 - Developing a viable MYC inhibitor for cancer treatment: a challenging journey from the lab to the clinic
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Dr Laura Soucek (CEO and PI, Peptomyc)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 23 May 2024

• 11:00 - Reimagining druggability using chemoproteomic platforms
  Join us in person or remotely via Teams
  Professor Dan Nomura (University of California, Berkeley)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 28 May 2024

• 12:00 - NEAT1 and paraspeckles: nuclear hubs regulating cellular stress responses
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Professor Maria Perander (The Arctic University of Norway)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 30 May 2024

• 12:00 - 18TH DAVID SMITH LECTURE: Genetics of neurodegeneration: progress towards mechanistic treatments
  18th DAVID SMITH LECTURE Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Professor Sir John Hardy (Chair of the Molecular Biology of Neurological Disease, UCL Institute of Neurology)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 4 June 2024

• 12:00 - Pharmacology Research Staff Society Seminar
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Pharamcology Research Staff Society
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Monday 10 June 2024

• 12:00 - New insights into smooth muscle peacemaking
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Professor Hikaru Hashitani (Department of Cell Physiology, Nagoya City University)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 11 June 2024

• 12:00 - Sleep for synaptic functions
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk
  Dr Julie Seibt (Surrey Sleep Research Centre, University of Surrey)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Thursday 19 September 2024

• 12:00 - Vascular effects of ion channels during healthy and complicated pregnancies
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Assistant Professor Ramón Lorca (Department of Obstetrics and Gynecology at The University of Colorado, Anschutz)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 15 October 2024

• 12:00 - Chemical tools to study molecular events at synapses
  Join us in person or online via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Associate Professor Frederic Menard (Department of Chemistry, University of British Columbia)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 22 October 2024

• 12:00 - The role of astrocytic chloride as modulator of neuronal inhibition in epilepsy
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Assistant Professor Verena Untiet (Center for Translational Neuromedicine, Copenhagen)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 29 October 2024

• 12:00 - Mycobacterium tuberculosis infection of host cells in space and time
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Maximiliano Gutierrez (Senior Group Leader, The Francis Crick Institute)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 5 November 2024

• 12:00 - Genomically driven discovery of novel cardiovascular signalling pathways
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Andrew Tinker (William Harvey Research Institute, Barts and the London School of Medicine )
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 12 November 2024

• 12:00 - Peroxisome dynamics and organelle interplay in health and disease
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Michael Schrader (Department of Biosciences, University of Exeter)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 19 November 2024

• 12:00 - Physics of cells and nanoscale bioparticles as a new biomarker for health and disease
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Assistant Professor Erdinc Sezgin (SciLifeLab Fellow, Karolinska Institute)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 26 November 2024

• 12:00 - Keeping the rhythm: how hERG potassium channels links genetics, drugs and pollution to cardiac arrhythmias
  This seminar has been cancelled
  Status: This talk has been cancelled
  Professor Jules Hancox (School of Physiology, Pharmacology & Neuroscience, University of Bristol)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 3 December 2024

• 12:00 - Brain-wide approaches to neuroplasticity and emotional behavior in the mouse
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Tommaso Pizzorusso (Professor of Physiology, Scuola Normale Superiore)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Wednesday 18 December 2024

• 12:00 - Leveraging the actinobacteria strain collection and genome database at NPDC for natural products and drug discovery
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Ben Shen (Natural Products Discovery Centre, UF Scripps Institute for Biomedical Innovation & Technology)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 21 January 2025

• 12:00 - Title tbc
  Join us in person or via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Greg James (Consultant Neurosurgeon, Neurovascular Service, Great Ormond Street Hospital)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 11 February 2025

• 12:00 - Title tbc
  Join us in person or remotely via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Dario DiFrancesco (The PaceLab, Department of Biosciences, University of Milan)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 18 February 2025

• 12:00 - Title tbc
  Join us in person or remotely via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Professor Mike Ludwig (University of Edinburgh)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars

Tuesday 11 March 2025

• 12:00 - Title tbc
  Join us in person or remotely via Teams - e-mail carolyn.thackrah@pharm.ox.ac.uk for joining instructions
  Dr Elena De Vita (Biologial and Behavioural Sciences, Queen Mary University of London)
  Pharmacology, Anatomical Neuropharmacology and Drug Discovery Seminars