• Type: Seminar Series
• Organising department: Department of Biochemistry

Monday 27 April 2015

• 13:00 - Shaping mitotic chromosomes
  Dr Christian Haering (EMBL)

Monday 11 May 2015

• 13:00 - Mechanism of protein transport into the endoplasmic reticulum
  Dr Ramanujan S. Hegde (MRC Laboratory of Molecular Biology)

Monday 22 June 2015

• 13:00 - Title TBC
  Professor Edith Heard, FRS (Professor College de France; Chair of Epigenetics and Cellular Memory. College de France and Director, Genetics and Developmental Biology Department, Institut Curie)

Friday 4 September 2015

• 11:00 - Unwrapping the function of histones during mitosis
  Professor Hironori Funabiki (Rockefeller University, New York)

Monday 7 September 2015

• 12:00 - Taste Processing in Drosophila
  Prof Kristin Scott (University of California, Berkeley)

Monday 21 September 2015

• 13:00 - 'How rotation is generated in the catalytic and membrane domains of F-TPases'
  Professor Sir John Walker, FRS, FMedSci (MRC Mitochondrial Biology Unit, Wellcome Trust/MRC Building, Cambridge)

Thursday 1 October 2015

• 11:00 - Tackling Tough Targets in Malaria: Fragment-Based Drug Discovery and Vaccines Against Disordered Antigens
  Prof Ray Norton (Monash University, Australia)

Friday 2 October 2015

• 01:25 - Graduate DPhil Symposium
  Various (See programme)

Monday 5 October 2015

• 13:00 - 'Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry'
  Professor Dr. Albert Heck (Professor of Biomolecular Mass Spectrometry and Proteomics, Utrecht University)

Monday 12 October 2015

• 13:00 - 'Looking at proteins in live cells with atomic resolution: from Science Fiction to Science Reality'
  Dr. Phil Selenko (Group Leader, In-cell NMR Spectroscopy, Leibniz Institute of Molecular Pharmacology, Berlin)
• 13:00 - Looking at proteins in live cells with atomic resolution: from Science Fiction to Science Reality
  Dr. Phil Selenko (Group Leader, In-cell NMR Spectroscopy, Leibniz Institute of Molecular Pharmacology, Berlin)

Monday 19 October 2015

• 13:00 - "Salmonella intracellular persisters and TA modules"
  Dr. Sophie Helaine (MRC Research Fellow, Imperial College)

Monday 30 November 2015

• 13:00 - "Kinetochores: from microtubule attachment to spindle assembly checkpoint signalling"
  Professor Dr. Andrea Musacchio (Director of the Department of Mechanistic Cell Biology at the Max-Planck Institute of Molecular Physiology in Dortmund, Germany)

Monday 14 December 2015

• 13:00 - "Staphylococcus aureus - A Super Bug! "
  Professor Simon Foster (Professor of Molecular Microbiology, University of Sheffield)

Monday 25 April 2016

• 13:00 - O-GlcNAc signalling in development and disease
  Professor Daan van Aalten, FRSE (Wellcome Trust Senior Fellow, MRC Protein Phosphorylation Unit and Division of Molecular Microbiology, University of Dundee)

Monday 23 May 2016

• 13:00 - D-Peptide Therapeutics: Empowering Nature’s Fragile Warriors
  Michael S. Kay, M.D., Ph.D. (University of Utah)

Thursday 23 June 2016

• 16:00 - Writing for success: positioning and engaging in the publication jungle
  Maria Cerrato Lara (Oxford Brookes University)

Friday 24 June 2016

• 11:00 - "Understanding the molecular logic of Adhesion GPCRs in mechanosensation"
  Professor Tobias Langenhan (University of Wuerzburg)

Tuesday 28 June 2016

• 11:00 - "The PCGF6-PRC1 complex suppresses premature activation of meiosis and germ cell related genes in ES cells"
  Professor Haruhiko Koseki (Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan)

Tuesday 5 July 2016

• 14:00 - Proteomics technologies and their application in biomedical research
  Prof. Dr. Matthias Mann (Director Dept. Proteomics and Signal Transduction, MPI, Germany)

Thursday 7 July 2016

• 13:00 - "Intrinsic disorder controls the function of p53 and other cancer-associated IDPs"
  Gary Daughdrill (University of South Florida)

Monday 15 August 2016

• 15:00 - “Towards a structural understanding of dual-pumping membrane-integral pyrophosphatases”
  Dr Nita Shah (Astbury Centre for Structural Molecular Biology, University of Leeds)

Wednesday 24 August 2016

• 14:00 - Cohesin in motion: single molecule imaging of the human cohesin complex on DNA
  TBA

Friday 2 September 2016

• 11:00 - Multi-scale modeling of chromosomal DNA from the base pair to the genome
  Dr Andrew Spakowitz (Stanford University)

Monday 19 September 2016

• 11:00 - Ess1: Traffic Cop of the Transcription Cycle
  Steven Hanes (SUNY-Upstate Medical University)

Monday 17 October 2016

• 13:00 - Gene regulation in chromatin
  Dr. Dirk Schübeler (Senior Group Leader, Friedrich Miescher Institute for Biomedical Research, Basel)

Tuesday 15 November 2016

• 09:30 - Special D. Phil Thesis Seminar: Probing the cohesin loading reaction using forward genetics and quantitative ChIP-seq
  TBA

Monday 5 December 2016

• 13:00 - Molecular Mechanisms involved in the Regulation of Appetite and Weight
  Professor Sadaf Farooqi PhD, FRCP, FMedSci (WT Senior Clinical Fellow and Professor of Metabolism and Medicine, University of Cambridge Metabolic Research Laboratories, Cambridge)

Thursday 8 December 2016

• 13:00 - Regulatory feedback from nascent RNA to transcription and chromatin modification
  TBA

Monday 9 January 2017

• 13:00 - Understanding the function and evolution of regulatory protein-RNA complexes
  Professor Jernej Ule (Professor of Molecular Neuroscience, The Francis Crick Institute, Department of Molecular Neuroscience, UCL Institute of Neurology, London)

Wednesday 11 January 2017

• 11:00 - New insight into the structure, function and dynamic of bacterial cell divisiion
  Professor Jie Xiao (John Hopkins University, Baltimore, USA)
• 12:00 - Kinetic UV cross-linking and analyses of cDNAs (xCRAC) reveals high-resolution dynamics of protein-RNA interactions in vivo
  Sander Granneman (Centre for Synthetic and Systems Biology (SynthSys), University of Edinburgh)

Thursday 12 January 2017

• 15:30 - The molecular mechanism and functional significance of GPS auto-proteolysis of adhesion-GPCRs: stories of EMR2/ADGRE2 and GPR56/ADGRG1
  Prof. Hsi-Hsien Lin (Chang Gung University, Taiwan)

Monday 16 January 2017

• 13:00 - "Gams to go: establishing and exploiting experimentally inducible sexual development in a malaria parasite"
  Professor A.P. Waters (Professor of Molecular and Developmental Parasitology, Wellcome Trust Principal Research Fellow, Director, Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow)

Friday 20 January 2017

• 12:00 - Early developmental program shapes colony morphology in bacteria
  Gideon Mamou (Hebrew University of Jerusalem, Israel)

Monday 6 February 2017

• 13:00 - Mitotic Checkpoint Kinases in Cancer Development and Treatment
  Prof. Dr. Rene H. Medema (Director of Research, Chairman Board of Directors, The Netherlands Cancer Institute, Amsterdam)

Thursday 30 March 2017

• 11:00 - Bacterial lipid trafficking and outer membrane homeostatis
  Shu-Sin Chng (National University of Singapore)

Monday 3 April 2017

• 13:00 - A new rationale for TF paralog evolution, expression and function
  Professor Matthias Merkenschlager (Lymphocyte Development Group, MRC Clinical Sciences Centre, London)

Tuesday 2 May 2017

• 11:00 - “The way is the goal: recognition and targeting of proteins by the Sec translocation machinery in bacteria”
  Dr Damon Huber (University of Birmingham)

Wednesday 10 May 2017

• 13:00 - Mechanics of the mitotic chromosome surface
  Dr. Daniel Wolfram Gerlich (Senior Research Group Leader, IMBA, Austria)

Monday 15 May 2017

• 16:00 - "ADP-ribosylation Site Identification: Discovery from Cancer to Virus"
  Professor Anthony Leung (MBiochem, Oxon) (John Hopkins University, Baltimore, USA)

Monday 12 June 2017

• 13:00 - Establishment and Maintenance of Specialised Chromatin Domains
  Professor Robin Allshire (Professor of Chromosome Biology, Wellcome Trust Centre for Cell Biology, University of Edinburgh)

Monday 3 July 2017

• 13:00 - Plasticity of neural circuits, from development to function
  Dr. Arantza Barrios (Research Associate, University College London)

Friday 29 September 2017

• 12:00 - 'From single molecules to single cells: Imaging nucleic acid enzymes at work'
  Professor David Rueda (Imperial College London)
• 13:25 - DPhil Symposium
  Various Speakers

Monday 23 October 2017

• 13:00 - Antisense transcription and epigenetic switching: lessons from FLC
  Professor Dame Caroline Dean (Project Leader, John Innes Centre, Norwich)

Monday 30 October 2017

• 17:00 - Evolutionary dynamics in the fungal symmetry breaking network
  Please note change of time: now at 5pm
  Dr. Liedewij Laan (Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, The Netherlands)

Monday 22 January 2018

• 13:00 - Lights, Camera, Action! Antimalarial drug discovery using a microscope
  Professor Jake Baum (Professor of Cell Biology and Infectious Diseases, Imperial College London)

Monday 12 March 2018

• 13:00 - Single cell Hi-C and single molecule imaging to study nuclear architecture
  Professor Ernest Laue (Professor of Structural Biology, Department of Biochemistry, University of Cambridge)

Monday 30 April 2018

• 13:00 - 'The remote control of gene expression'
  Professor Wendy Bickmore, FRS, FMedSci (Director: MRC Human Genetics Unit, IGMM, University of Edinburgh)

Monday 11 June 2018

• 13:00 - Cellular responses to DNA damage: translating molecular insights towards new cancer therapies
  Professor Steve Jackson, PhD, FRS, FMedSci (Frederick James Quick Professor of Biology, The Gurdon Institute, Cambridge)

Monday 2 July 2018

• 13:00 - Mitosis, genome stability and cancer chemotherapy
  Professor Stephen Taylor (Leech Professor of Pharmacology, Manchester Cancer Research Centre, University of Manchester)

Thursday 27 September 2018

• 08:30 - Graduate Student Induction
  Various Speakers

Friday 28 September 2018

• 13:30 - DPhil Symposium
  Various Speakers

Tuesday 24 September 2019

• 14:00 - Regulation of the DNA interstrand crosslink repair throught FANCD2 phosphorylation
  Marian Kupculak (Cell Biology, Development and Genetics,University of Oxford)
• 14:30 - Expanding the utility of peptide for dual function in purification and conjugation
  Irsyad Khairil Anuar (Cell Biology, Development and Genetics, Department of Biochemistry, University of Oxford)
• 15:00 - Revealing Secrets Hiding in Plain Sight: Advances in Multi-scale Multi-modal Imaging
  Mark H. Ellisman (Distinguished Professor of Neurosciences; Director, the National Center for Microscopy and Imaging Research (NCMIR), UC San Diego)

Tuesday 15 October 2019

• 10:00 - Versatile Tools Towards Real-time, Single- molecule and Single-Cell Biology
  Dr. Aida Llauró-Portell (LUMICKS)

Monday 24 May 2021

• 13:00 - "Replication and Repair: the faces of BRCA1"
  Professor Jo Morris PhD BSc (Professor of Molecular Genetics, Institute of Cancer and Genomic Sciences, University of Birmingham)

Monday 21 November 2022

• 13:00 - Of yeast and Man: Kinetochore Structures and Function
  Stanislau Yatskevich (LMB, Cambridge)

Tuesday 7 March 2023

• 15:30 - The physiological purpose for DNA repair in us - from gin and tonics to formalin pots
  Prof. K.J. Patel (MRC Weatherall Institute of Molecular Medicine)

Thursday 9 March 2023

• 15:00 - Understanding the mechanism and regulation of Eukaryotic DNA replication
  Dr. John Diffley, FMedSci, FRS (Associate Research Director, The Francis Crick Institute)

Thursday 30 November 2023

• 14:00 - Activation of an origin of replication visualised by cryo-EM
  Alessandro Costa (The Francis Crick Institute)

Monday 22 April 2024

• 13:00 - "Controlling Aurora-A kinase functions in mitosis and cancer"
  Professor Richard Bayliss (Professor of Molecular Medicine, The Astbury Centre for Structural Molecular Biology, University of Leeds)

Monday 29 April 2024

• 13:00 - 'Targeting DNA methyltransferases to chromatin: a tale of two N- terminal regions’
  Dr. Marcus Wilson (Henry Dale Fellow / Academic Lead cryo-EM Facility, Wellcome Centre for Cell Biology, University of Edinburgh)

Monday 20 May 2024

• 13:00 - ‘Protons to Patients: insights into lysosomal pH regulation from novel disease to lipid regulators’
  Dr. Joseph Mindell (Senior Investigator, Membrane Transport Biophysics Section, NIH NINDS, USA)

Thursday 27 June 2024

• 10:00 - Controlling MAC pore formation
  TBA

Monday 28 October 2024

• 13:00 - 'The endocytic clathrin adaptor complex AP2: From crystallography via SPA and CET to SIM TIRF'
  Professor David Owen (Professor of Structural and Molecular Biology, Cambridge Institute for Medical Research)

Monday 4 November 2024

• 13:00 - 'The role of cytoskeleton dynamics in bacterial cell division'
  Professor Seamus Holden (Professor of Microbial Biophysics, University of Warwick)

Monday 11 November 2024

• 13:00 - 'Nucleosomes at the Dawn of Eukaryotes'
  Professor Tobias Warnecke (Dept. of Biochemistry, University of Oxford)

Monday 18 November 2024

• 13:00 - 'Non-canonical functions of DNA methylation in mammals'
  Maxim Greenberg (Institut Jacques Monod, France)

Monday 25 November 2024

• 13:00 - 'Use of the cytoskeleton to control Shigella infection'
  Dr. Serge Mostowy (Department of Infection Biology, London School of Hygiene & Tropical Medicine)

Monday 2 December 2024

• 13:00 - The developmental biology of cancer
  Professor Richard White (Oxford Ludwig Institute)

Monday 20 January 2025

• 13:00 - A Contractile injection system mediates development and cell death in multicellular bacteria
  Dr. Susan Schlimpert (Group Leader, Royal Society University Research Fellow, John Innes Centre)

Monday 27 January 2025

• 13:00 - 'Chromatin Regulation and Cancer'
  Professor Yang Shi (Ludwig Institute, University of Oxford)

Monday 17 February 2025

• 13:00 - Moves and mechanisms of Wnt pathway tumor suppressor proteins: from basic insights to applications
  Professor Madelon Maurice (Professor of Molecular Cell Biology, Department of Cell Biology UMC Utrecht)

Monday 24 February 2025

• 13:00 - Cellular functionality and plasticity in the senescence spectrum
  Professor Masashi Narita (Group Leader, CRUK, Cambridge Institute)

Monday 3 March 2025

• 13:00 - Spatiotemporal control of symmetry-breaking in development: lessons from the C. elegans embryo
  Dr. Nathan Goehring (Senior Group Leader, The Francis Crick Institute, London)

Monday 10 March 2025

• 13:00 - “Minimization of the Bacillus subtilis replication origin reveals distinct modules for initiator delivery, DNA unwinding, and helicase activation”
  Professor Heath Murray (Professor of Bacterial Genetics, Centre for Bacterial Cell Biology, Newcastle University)

Monday 28 April 2025

• 13:00 - Lipid mediators in the pathogenesis of dengue
  Professor Neelika Malavige (Dept. of Immunology and Molecular Medicine, University of Sri Jayewardenepura, Sri Lanka)

Monday 12 May 2025

• 13:00 - Title TBC
  Professor James Naismith (Head of MPLS, University of Oxford)

Monday 19 May 2025

• 13:00 - Title TBC
  Dr. Veronique Azuara (Reader in Stem Cell Biology, Department of Metabolism, Digestion and Reproduction - Faculty of Medicine, Imperial College)

Monday 2 June 2025

• 13:00 - Title TBC
  Dr. Z. (Tzviya) Zeev Ben Mordehai (Associate Professor, Utrecht University)

Monday 9 June 2025

• 13:00 - Title TBC
  Professor Judy Hirst, FRS, FMedSci (Professor of Biological Chemistry, MRC Mitochondrial Biology Unit, University of Cambridge)

Monday 16 June 2025

• 13:00 - Title TBC
  Dr. Elisa Fadden (Associate Professor in Pharmacology, University of Southampton)

Monday 13 October 2025

• 13:00 - Title TBC
  Dr. Giacomo Cavalli (Institute of Human Genetics, France)

Monday 19 January 2025

• 13:00 - TBC
  Dr Simon Boulton (The Francis Crick Institute, London)

Monday 2 February 2025

• 13:00 - TBC
  Prof Julie Welburn (Wellcome Centre for Cell Biology, The University of Edinburgh)