• Type: Seminar Series
• Organising department: Department of Biochemistry

Friday 26 February 2016 (6th Week, Hilary Term)

• 14:00 - "Divorcing chromosomes still need rings: the role of an SMC protein in chromosome segregation in Caulobacter crescentus"
  Dr Tung Le (Department of Molecular Microbiology, John Innes Centre, Norwich)

Thursday 17 March 2016 (9th Week, Hilary Term)

• 11:00 - "Linking histone and DNA recognition to the epigenetic inheritance of DNA methylation"
  Professor Brian Strahl (Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, USA)

Monday 11 April 2016 (-1st Week, Trinity Term)

• 10:00 - 'Atomic structure of human γ-secretase'
  Dr. Xiao-Chen Bai (MRC, LMB, Cambridge)
• 11:00 - 'Architecture of mTOR complex 1'
  Dr. Christopher Aylett (IMBB, ETH Zürich, Switzerland)

Wednesday 4 May 2016 (2nd Week, Trinity Term)

• 14:00 - "Organizing chromosomes for segregation: the dynamic structure of the bacterial SMC complex"
  TBA

Friday 1 July 2016 (10th Week, Trinity Term)

• 14:30 - "Chromosome organization by SMC complexes: linking sisters and extruding loops”
  Dr. Benjamin Rowland (Research Associate, Netherlands Cancer Institute)

Tuesday 22 November 2016 (7th Week, Michaelmas Term)

• 09:00 - Protein signalling in genome maintenance pathways
  Ian Gibbs-Seymour (University of Oxford)
• 09:45 - Measure, Model, Manipulate: single cell imaging to understand proliferation in health and disease
  Alexis Barr (Institute of Cancer Research, UK)
• 11:00 - Single molecular imaging approaches to study SMC function in vitro
  Iain Davidson (Research Institute of Molecular Pathology, Vienna)
• 11:45 - Molecular mechanisms and organization of membranes from synthetic endosomes
  David Murray (Max Planck Institute, Germany)
• 12:30 - Regulation of Met1 (linear) linked polyubiquitin chains
  Paul Elliott (MRC Laboratory of Molecular Biology, UK)

Wednesday 18 January 2017 (1st Week, Hilary Term)

• 14:00 - Orchestrating mRNA processing in sex determination, neuronal development and function
  Dr Matthias Soller (School of Biosciences, University of Birmingham)

Wednesday 1 March 2017 (7th Week, Hilary Term)

• 18:00 - Inspiring Innovation: Bringing Academia and Industry at The Royal Society
  Katy Gearing (Head of Industry Engagement, Royal Society), Alasdair Taylor (Industry Programme Manager at the Royal Society)

Monday 13 March 2017 (9th Week, Hilary Term)

• 17:30 - Enterprising Oxford: The Inside Story
  Anne Miller (MPLS), Leah Thompson (MPLS Division)

Tuesday 21 March 2017 (10th Week, Hilary Term)

• 18:00 - Meet the CEO
  Hosted by Science Innovation with permission from the Department of Biochemistry. Access to the building will granted by hosts at the door.
  Catherine Bottrill (Pilio), Ekaterina Damer (Prolific Academic Ltd.), John Stuart (Bounts Ltd.)

Monday 10 April 2017 (-1st Week, Trinity Term)

• 17:00 - Alternative Careers: A Roundtable Discussion with Naturejobs
  Hosted by Science Innovation Union with permission from Department of Biochemistry
  Jack Leeming (Nature Publishing Group)

Monday 15 May 2017 (4th Week, Trinity Term)

• 17:30 - Meet the CEO
  The seminar is hosted by Science Innovation Union (science-union.org) with permission from Department of Biochemistry
  Riham Satti (MeVitae), John Stuart (Bounts Ltd.), Ekaterina Damer (Prolific Academic Ltd.)

Friday 19 May 2017 (4th Week, Trinity Term)

• 10:30 - Mechanism of molecular motors in mitotic spindle formation and positioning
  Dr. Julie Welburn (Wellcome Trust Centre for Cell Biology, University of Edinburgh)
• 11:05 - Chemical physiology of protein conjugates and natural products
  Dr. Gonçalo Bernardes (Department of Chemistry, University of Cambridge)
• 11:40 - Adhesion GPCRs: from complex structures to cellular functions
  Dr. Elena Seiradake (Department of Biochemistry, University of Oxford)

Wednesday 28 June 2017 (10th Week, Trinity Term)

• 12:00 - 'Chromatin-based Epigenetic Inheritance'
  Dr. Lars E.T.Jansen (Laboratory for Epigenetic Mechanisms, Portugal)

Thursday 29 June 2017 (10th Week, Trinity Term)

• 15:30 - "Role of MatP in post-replicative cohesion of E. coli ter"
  Dr Estelle Crozat-Brendon (Biological and Soft Systems, Department of Physics, Cavendish Laboratory, University of Cambridge)

Wednesday 5 July 2017 (11th Week, Trinity Term)

• 09:00 - ‘Targeting transcription through disruption of BET complexes’
  Dr. Panagis Filippakopoulos (SGC, University of Oxford)
• 09:35 - 'Unusual RNA/DNA structures in health and disease'
  Dr. Natalia Gromak (Group Leader, Dunn School of Pathology, Oxford)
• 10:20 - 'Mechanical Forces Induce Mitochondrial Fission'
  Professor Benoit Kornmann (ETH Zurich, Switzerland)
• 10:55 - ‘Molecular Mechanisms in Brain Development’
  Dr. Elena Seiradake (Department of Biochemistry, University of Oxford)
• 11:30 - ‘Biology in solution: from the atomic scale to mechanistic biochemistry’
  Dr. Sylvia McLain (Department of Biochemistry, Oxford)

Saturday 16 September 2017 (21st Week, Trinity Term)

• 11:00 - The blurred boundary between coding and non-coding RNA
  Dr. Julie Aspden (University of Leeds)

Monday 11 December 2017 (10th Week, Michaelmas Term)

• 10:00 - 'Using genome-wide protein tagging to uncover new flagellum biology: Proximal/distal flagellum structure asymmetry controls swimming behaviours in eukaryotic parasites'
  Dr. Richard J. Wheeler (Sir Henry Wellcome Post-doctoral Fellow, Sir William Dunn School of Pathology and Max Planck Institute of Molecular Cell Biology and Genetics, Dresden)

Tuesday 27 February 2018 (7th Week, Hilary Term)

• 09:00 - Organelle contact sites: what are they, what are they good for, and how can they be bad
  Professor Benoit Kornmann (ETH Zurich, Switzerland)
• 09:35 - 3D Chromatin Conformation during early Embryonic Development
  Dr. Juanma Vaquerizas (MPI for Molecular Biomedicine, Germany)
• 10:10 - Defining Centriole Function in Centrosome and Cilium Biogenesis
  Dr. Alexander Dammermann (Max F Perutz Laboratories, Austria)
• 11:00 - Bifidobacterium: a Key Early Life Microbiota Member
  Dr. Lindsay Hall (Quadram Institute Bioscience, Norwich)
• 11:35 - Plant Cysteine Oxidases: Novel Targets for Future Food Security?
  Dr. Emily Flashman (Chemistry Research Laboratory, Oxford)

Monday 9 April 2018 (-1st Week, Trinity Term)

• 11:00 - 'Cell-cell interactions in microbial communities: from model systems to the microbiome'
  Professor Kevin Foster (Professor of Evolutionary Biology, Department of Zoology, Oxford)

Wednesday 11 April 2018 (-1st Week, Trinity Term)

• 12:00 - Science communication & public engagement
  Alison Brindle (Medical Sciences Division, University of Oxford), Naomi Gibson (Medical Sciences Division)

Thursday 19 April 2018 (0th Week, Trinity Term)

• 10:30 - ‘Probing Chaperone-assisted peptide exchange dynamics of Major Histocompatibility Complex molecules by NMR’
  Dr. Nikolaos Sgourakis (University of California, US)
• 11:05 - ‘A Phylogenetic Profiling Approach To Identifying Novel Ciliogenesis Genes’
  Professor Alexander Dammermann (University of Vienna, Austria)
• 14:25 - 'Single molecule imaging of nucleosome dynamics during DNA replication in Xenopus egg extracts'
  Dr. Dominika Gruszka (Crick Institute, London)
• 15:00 - ‘TIE proteins: the chemical harpoons of Gram-positive bacteria’
  Dr. Ulrich Schwarz-Linek (University of St. Andrews, St. Andrews)
• 15:50 - ‘Cell shape formation controlled by cytoskeleton’
  Dr. Naoko Mizuno (MPI Fur Biochemie, Germany)
• 16:25 - ‘Biogenesis of the Bacterial Cell Envelope’
  Dr Phillip Stansfeld (Department of Biochemistry, Oxford University)

Wednesday 12 September 2018 (21st Week, Trinity Term)

• 15:00 - Biochem to billions Introduction event: (anyone can attend)
  Prof Mark Howarth (University of Oxford Department of Biochemistry), Professor Jane Mellor (University of Oxford)

Wednesday 26 September 2018 (-1st Week, Michaelmas Term)

• 10:30 - Centrosomes: ubiquitious organelles with tissue-specific functions?
  Dr. Fanni Gergely (Senior Group Leader, CRUK Cambridge Institute, University of Cambridge)
• 14:00 - Biochem to billions Pitching and investing event: (only members of the Department can attend)
  Various Speakers

Thursday 4 October 2018 (0th Week, Michaelmas Term)

• 11:00 - "Imaging spatiotemporal regulation of immune signalling at the plasma membrane"
  Dr. Erdinc Sezgin (Postdoctoral Scientist, Weatherall Institute of Molecular Medicine, University of Oxford)

Friday 12 October 2018 (1st Week, Michaelmas Term)

• 11:00 - Codon choice is the dominant determinant of mRNA levels in trypanosomes
  Prof. Mark Carrington (University of Cambridge)

Tuesday 19 February 2019 (6th Week, Hilary Term)

• 14:00 - Introduction to the Molecular Biophysics Suite
  Dr David Staunton (Department of Biochemistry)

Friday 5 April 2019 (12th Week, Hilary Term)

• 11:00 - “Cryo-EM snapshots of the catalytic spliceosome - and RNA heart in a malleable protein body”
  Dr. Sebastian Fica (MRC, LMB, Cambridge)

Wednesday 5 June 2019 (6th Week, Trinity Term)

• 14:00 - Illuminating the Molecular Choreography of Multi-segmented Viral Genomes
  Dr Alex Borodavka (Astbury Centre for Structural Molecular Biology, University of Leeds)

Wednesday 11 September 2019 (20th Week, Trinity Term)

• 08:45 - “Molecular Diversity in Regulating Bacterial Potassium Uptake”
  Dr. Inga Hanelt (Goethe-University, Frankfurt)
• 09:20 - “The Mycobacterium ulcerans exotoxin, mycolactone: a novel inhibitor of Sec61-dependent translocation that drives Buruli ulcer pathogenesis”
  Dr. Rachel Simmonds (University of Surrey)
• 09:55 - “Epigenetic inheritance: the curious case of the human centromere”
  Dr. Lars Jansen (Wellcome Trust Senior Research Fellow, Dept. of Biochemistry, Oxford University)
• 10:45 - “Sweet coats: Diverse mechanisms of microbial polysaccharide secretion”
  Professor Jochen Zimmer (University of Virginia)
• 11:20 - "To divide or not to divide: The interplay of cell cycle decision-making and post-translational modifications"
  Dr. Joerg Mansfeld (Technische Universitat Dresden)

Tuesday 22 October 2019 (2nd Week, Michaelmas Term)

• 16:00 - World Synthetic Biology championships- the Oxford team's experience, and their project "Empowering probiotics with quorum sensing abilities to treat C. difficile infection"
  Oxford iGEM team (University of Oxford)

Wednesday 23 October 2019 (2nd Week, Michaelmas Term)

• 09:00 - “Dissecting RNA Localisation and Local Translation in Neurons”
  Dr. Marina Chekulaeva (Berlin Institute for Medical Systems Biology, Germany)
• 09:35 - “Mechanism of Nitrogenase: Electrocatalysis at a Dinuclear Active Site”
  Professor Oliver Einsle (Institute for Biochemistry, Albert-Ludwigs-Universitat Freiburg, Germany)
• 10:10 - “Functional organelle remodeling during adipocyte differentiation”
  Dr. Robin Klemm (Institute of Molecular Sciences, University of Zurich)
• 10:55 - “Understanding how cellular RNA-binding proteins control virus infection”
  Dr Alfredo Castello Palomares (Department of Biochemistry, University of Oxford)
• 11:30 - "Regulation of vesicle acidification at the neuronal synapse"
  Professor Ira Milosevic (European Neuroscience Institute - max Planck Society and University Medical Center Gottingen Joint Initiative, Gottingen)

Monday 4 November 2019 (4th Week, Michaelmas Term)

• 08:45 - “Tuning gears for the tubulin motor: insights from in vitro reconstitution”
  Dr. Vladimir Volkov (Delft University of Technology, Netherlands)
• 09:35 - “Exon-centric functional genomics uncovers splice variants underlying normal physiology & disease-related phenotypes”
  Dr. Thomas Gonatopoulos-Pournatzis (Blencowe Laboratory, University of Toronto)
• 10:35 - "Towards anti-resistance antimicrobial chemotherapeutic strategies using large-scale chemical-genetics”
  Dr. Eachan Johnson (Broad Institute of MIT and Harvard, US)
• 11:25 - "Viral manipulation of information transfer in biology: structural and functional insights"
  Dr. Chris Hill (Queen's College, Cambridge)
• 12:15 - “The role of mobile DNA in spreading antimicrobial resistance and virulence”
  Dr. Ana Cehovin (Sir William Dunn School of Pathology, University of Oxford)
• 14:00 - “Modelling the dynamic organisation of complex cell membranes: from the nano to the meso scale”
  Dr Anna Duncan (University of Oxford)

Friday 24 January 2020 (1st Week, Hilary Term)

• 12:00 - Top tips on careers & fellowship applications for early career researchers
  Dr Candace Hassall, Head of Researcher Affairs (Wellcome Trust)

Friday 21 February 2020 (5th Week, Hilary Term)

• 10:00 - Wellcome Structural Biology course: Introduction to facility. Characterisation and Stability
  Dr David Staunton (Department of Biochemistry)
• 11:15 - Wellcome Structural Biology course: Affinity and kinetics
  Dr David Staunton (Department of Biochemistry)

Wednesday 18 March 2020 (9th Week, Hilary Term)

• 14:00 - How to make the most of your Biacore instrument?
  Status: This talk has been cancelled
  Annete Persson (GE Healthcare)

Friday 25 June 2021 (9th Week, Trinity Term)

• 14:00 - “How dynein and dynactin transport different cargos along microtubules”
  Dr. Clinton Lau (Carter Laboratory, MRC Laboratory of Molecular Biology, Cambridge)

Monday 13 March 2023 (9th Week, Hilary Term)

• 15:00 - "Genome organization and long noncoding RNAs control the timing of Hox gene transcription during development"
  Dr. Philippe J. Batut (Levine Lab, Princeton)

Wednesday 17 April 2024 (0th Week, Trinity Term)

• 11:00 - 'Visualising the molecular mechanisms of eukaryotic DNA replication'
  Dr. Morgan Jones (Staff Scientist, Yeeles Lab, MRC LMB Cambridge)

Friday 17 May 2024 (4th Week, Trinity Term)

• 14:00 - ‘Mechanism for Membrane Protein Insertion and Complex Assembly’
  Dr. Haoxi Wu (Postdoctoral Fellow, Hegde Lab, MRC Laboratory of Molecular Biology, Cambridge)

Tuesday 25 June 2024 (10th Week, Trinity Term)

• 11:30 - 'Allosteric mechanisms of cellular stress response'
  Dr. Rosalie Lawrence (Jane Coffin Childs Postdoctoral Fellow, Peter Walter Lab, UCSF)