Professor Sir John Hardy is the Chair of Molecular Biology of Neurological Disease at the UCL Institute of Neurology with over 23,000 citations. In recognition of his exceptional contributions to science, he was elected a Fellow of the Royal Society in 2009. In 2022 he was awarded a Knighthood in New Year’s honours in recognition of contributions to human health and dementia research. His research interests are in the genetic analysis of disease; historically, working on the genetic analysis of Alzheimer’s disease and other dementias and, more recently, on Parkinson’s disease and other movement disorders and, most recently on motor neuron disease.